Statistical Methods in Drug Combination Studies

Author:   Wei Zhao ,  Harry Yang
Publisher:   Taylor & Francis Inc
Volume:   69
ISBN:  

9781482216745


Pages:   240
Publication Date:   19 December 2014
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Statistical Methods in Drug Combination Studies


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Full Product Details

Author:   Wei Zhao ,  Harry Yang
Publisher:   Taylor & Francis Inc
Imprint:   Chapman & Hall/CRC
Volume:   69
Dimensions:   Width: 15.60cm , Height: 1.80cm , Length: 23.40cm
Weight:   0.470kg
ISBN:  

9781482216745


ISBN 10:   1482216744
Pages:   240
Publication Date:   19 December 2014
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Drug Combination: Much Promise and Many Hurdles. Drug Combination Synergy. Drug Combination Design Strategies. Confidence Interval for Interaction Index. Two-Stage Response Surface Approaches to Modeling Drug Interaction. A Bayesian Industry Approach to Phase I Combination Trials in Oncology. Statistical Methodology for Evaluating Combination Therapy in Clinical Trials. Challenges and Opportunities in Analysis of Drug Combination Clinical Trial Data. Software and Tools to Analyze Drug Combination Data.

Reviews

This book is a welcome addition to the literature and fills a needed niche since last book written on drug synergism was over 15 years ago . . . each chapter presents a different technique for solving common challenges in the development of drug combinations. . . Overall, this book serves as a good reference for both researchers in the field of statistics and drug combination development. ~ Jessica L. Jaynes, California State University, Fullerton Investigating drug combinations is a steadily growing area in preclinical and clinical research.As usual, specific statistical methodology is needed to handle these kinds of trials. . . .the book is generallywell structured and the majority of sections actually builds up on and refers to each other. This book provides a good overview on and a good introduction to the topic of statistical methods for drug combination studies, especially regarding the preclinical part. ~ Tim Holland-Letz, German Cancer Research Center Heidelberg


This book is a welcome addition to the literature and fills a needed niche since last book written on drug synergism was over 15 years ago . . . Overall, this book serves as a good reference for both researchers in the field of statistics and drug combination development. ~ Jessica L. Jaynes, California State University, Fullerton Investigating drug combinations is a steadily growing area in preclinical and clinical research.As usual, specific statistical methodology is needed to handle these kinds of trials. . . .the book is generallywell structured and the majority of sections actually builds up on and refers to each other. This book provides a good overview on and a good introduction to the topic of statistical methods for drug combination studies, especially regarding the preclinical part. ~ Tim Holland-Letz, German Cancer Research Center Heidelberg This book is a welcome addition to the literature and fills a needed niche since last book written on drug synergism was over 15 years ago . . . each chapter presents a different technique for solving common challenges in the development of drug combinations. . . Overall, this book serves as a good reference for both researchers in the field of statistics and drug combination development. ~ Jessica L. Jaynes, California State University, Fullerton Investigating drug combinations is a steadily growing area in preclinical and clinical research.As usual, specific statistical methodology is needed to handle these kinds of trials. . . .the book is generallywell structured and the majority of sections actually builds up on and refers to each other. This book provides a good overview on and a good introduction to the topic of statistical methods for drug combination studies, especially regarding the preclinical part. ~ Tim Holland-Letz, German Cancer Research Center Heidelberg


This book is a welcome addition to the literature and fills a needed niche since last book written on drug synergism was over 15 years ago ... each chapter presents a different technique for solving common challenges in the development of drug combinations... Overall, this book serves as a good reference for both researchers in the field of statistics and drug combination development. ~ Jessica L. Jaynes, California State University, Fullerton


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Wei Zhao, Harry Yang

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