Overview

Neuronal communication forms the basis for all behavior, from the smallest movement to our grandest thought processes. Among the many mechanisms that support these functions, spike timing is among the most powerful and—until recently—perhaps the least studied. In the last two decades, however, the study of spike timing has exploded. The heightened interest is due to several factors. These include the development of physiological tools for measuring the activity of neural ensembles and analytical tools for assessing and characterizing spike timing. These advances are coupled with a growing appreciation of spike timing’s theoretical importance for the design principles of the brain. Spike Timing: Mechanisms and Function examines the function of spike timing in sensory, motor, and integrative processes, providing readers with a broad perspective on how spike timing is produced and used by the nervous system. It brings together the work and ideas of leaders in the field to address current thinking as well as future possibilities. The first section of the book describes the foundation for quantitative analysis and theory. It examines the information contained in spike timing, how it can be quantified, and how neural systems can extract it. The second section explores how input-output relationships are reflected in spike timing across a range of sensory systems. Drawing together multiple perspectives, including theoretical and computational studies as well as experimental studies in a range of model systems, the book provides a firm background for investigators to consider spike timing as it applies to their own work. It also offers a glimpse of future advances related to mechanisms of spike timing and its role in neural function, such as the development of novel computational technologies.

Full Product Details

Author:   Patricia M. DiLorenzo ,  Jonathan D. Victor
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:   53
Dimensions:   Width: 15.60cm , Height: 2.80cm , Length: 23.40cm
Weight:   0.793kg
ISBN:  

9781439838150

ISBN 10:   1439838151
Pages:   462
Publication Date:   02 May 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Introduction. SPIKE TIMING - TOOLS AND MODELS. Spike Trains as Event Sequences: Fundamental Implications. Neural Coding and Decoding with Spike Times. Can We Predict Every Spike? Statistical Identification of Synchronous Spiking. Binless Estimation of Mutual Information in Metric Spaces. Measuring Information in Spike Trains about Intrinsic Brain Signals. The Role of Oscillation-Enhanced Neural Precision in Information Transmission between Brain Areas. SPIKE TIMING - CODING, DECODING AND SENSATION. Timing Information in Insect Mechanosensory Systems. Neural Encoding of Dynamic Inputs by Spike Timing. Relating Spike Times to Perception – Auditory Detection and Discrimination. Spike Timing and Neural Codes for Odors. Spike Timing as a Mechanism for Taste Coding in the Brainstem. Increases In Spike Timing Precision Improves Gustatory Discrimination Upon Learning. Spike Timing in Early Stages of Visual Processing. Cortical Computations Using Relative Spike Timing.

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Author Information

Patricia M. Di Lorenzo is Professor and Director of the Undergraduate Program in Psychobiology at Binghamton University, New York. Jonathan D. Victor is Fred Plum Professor of Neurology at Weill Medical College of Cornell University, New York.

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