Specificity, Function, and Development of NK Cells: NK Cells: The Effector Arm of Innate Immunity
Author:   Klas Kärre ,  Marco Colonna
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   Softcover reprint of the original 1st ed. 1998
Volume:   230
ISBN:  

9783642468612


Pages:   248
Publication Date:   08 March 2012
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Specificity, Function, and Development of NK Cells: NK Cells: The Effector Arm of Innate Immunity


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Overview

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.

Full Product Details

Author:   Klas Kärre ,  Marco Colonna
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1998
Volume:   230
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   0.406kg
ISBN:  

9783642468612


ISBN 10:   3642468616
Pages:   248
Publication Date:   08 March 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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