Overview
Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research in bioorganic chemistry. Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries addresses the exciting expectation that solid-phase assembly of oligosaccharides will have a fundamental impact on the field of glycobiology. This publication details the methodologies currently investigated for the attachment of carbohydrates to beads, synthesis including coupling strategies, and removal of the product from beads. With chapters written by eminent contributing authors, the material explores different synthetic strategies, glycosylation protocols, the use of solid supports versus soluble polymeric supports, and ""on-resin"" analytical methods. Tremendous progress in the field has set the stage for Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries to provide a wealth of information on such topics as: Specific oligosaccharide structures used in signal transduction processes Preparation and screening of glycopeptide libraries Solid-phase carbohydrate synthesis
Full Product Details
Author: Peter H. Seeberger (Department of Chemistry, Massachusetts Institute of Technology, 18-211, 77 Massachusetts Avenue, Cambridge, MA 02139, USA)
Publisher: John Wiley & Sons Inc
Imprint: Wiley-Interscience
Dimensions:
Width: 16.20cm
, Height: 2.00cm
, Length: 24.60cm
Weight: 0.583kg
ISBN: 9780471378280
ISBN 10: 0471378283
Pages: 320
Publication Date: 21 August 2001
Audience:
College/higher education
,
Professional and scholarly
,
Undergraduate
,
Postgraduate, Research & Scholarly
Format: Hardback
Publisher's Status: Active
Availability: Out of stock
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.
Reviews
"""a splendid overview over the state of the art of the field"" (Perkin Transactions, No.23, 2001) ""a valuable addition to the reference literature"" (Synthesis, No. 5, 2002)"
a splendid overview over the state of the art of the field (Perkin Transactions, No.23, 2001) a valuable addition to the reference literature (Synthesis, No. 5, 2002)
""a splendid overview over the state of the art of the field"" (Perkin Transactions, No.23, 2001) ""a valuable addition to the reference literature"" (Synthesis, No. 5, 2002)
a splendid overview over the state of the art of the field (Perkin Transactions, No.23, 2001) a valuable addition to the reference literature (Synthesis, No. 5, 2002)
Author Information
PETER H. SEEBERGER is Firmenich Assistant Professor of Chemistry at the Massachusetts Institute of Technology in Cambridge, Massachusetts.
