Overview

This book is part of a series dedicated to providing researchers in the field with validated and tested methodologies for the solid phase synthesis of interesting and biologically relevant molecules. The third volume focuses on microwave-assisted solid-phase organic synthesis, and provides an overview of microwave-assisted organic synthesis (MAOS), showcasing the effect of combining Nobel Prize winning SPOS with microwave irradiation. The volume is divided into 11 parts offering highlights from the field through various aspects: transition metal catalysis (Part 1), substitution reactions (Part 2), condensation reactions (Part 3), rearrangemetns (Part 4), cleavage reactions (Part 5), multi-component reactions (Part 6), peptide and peptidomimetics synthesis (Part 7), polymer-supported reagents (Part 8), polymer-supported catalysis (Part 9), polymer-supported scavengers (Part 10), and special topics like nanoparticle synthesis and catalysis (Part 11). Each Part includes a comprehensive collection of reactions and transformations, explaining their procedures, benefits, and techniques, such as the solution-phase synthetic advantages of using polymer-supported reagents (PSR), reducing metal contamination of reaction mixture and product with immobilized catalysts on polymer supports, and solvent-free MAOS green chemistry.

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9781118430712

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