Small-Molecule Inhibitors of Protein-Protein Interactions
Author:   Lyubomir Vassilev ,  David Fry
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2011 ed.
Volume:   348
ISBN:  

9783642170829


Pages:   174
Publication Date:   12 January 2011
Format:   Hardback
Availability:   In Print   Availability explained
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Small-Molecule Inhibitors of Protein-Protein Interactions


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Overview

In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches, and share experiences, results, thoughts, and opinions. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. Ultimately, there are numerous lessons to be taken away from this collection, and the editors hope that this snapshot of the current state of the art in developing protein-protein inhibitors not only pays tribute to the past successes, but also generates excitement about the future potential of this field

Full Product Details

Author:   Lyubomir Vassilev ,  David Fry
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2011 ed.
Volume:   348
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   0.481kg
ISBN:  

9783642170829


ISBN 10:   364217082
Pages:   174
Publication Date:   12 January 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Preface.- Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.- Small-molecule inhibitors of IL-2/IL-2R: lessons learned and applied.- Small Molecule Inhibitors of the Human Papillomavirus E1-E2 Interaction.- Design of small-molecule Smac mimetics as IAP antagonists.- Small-molecule inhibitors reveal a new function for Bcl-2 as a pro-angiogenic signaling molecule.- Small-molecule modulators of c-Myc/Max and Max/Max interactions.-  Small-molecule inhibitors of the p53-MDM2 interaction.- Subject index

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