Small-Molecule Inhibitors of Protein-Protein Interactions

Author:   Lyubomir Vassilev ,  David Fry
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2011 ed.
Volume:   348
ISBN:  

9783642266706


Pages:   174
Publication Date:   27 February 2013
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Small-Molecule Inhibitors of Protein-Protein Interactions


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Overview

In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches, and share experiences, results, thoughts, and opinions. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. Ultimately, there are numerous lessons to be taken away from this collection, and the editors hope that this snapshot of the current state of the art in developing protein-protein inhibitors not only pays tribute to the past successes, but also generates excitement about the future potential of this field

Full Product Details

Author:   Lyubomir Vassilev ,  David Fry
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2011 ed.
Volume:   348
Dimensions:   Width: 15.50cm , Height: 1.00cm , Length: 23.50cm
Weight:   0.296kg
ISBN:  

9783642266706


ISBN 10:   3642266703
Pages:   174
Publication Date:   27 February 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface.- Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.- Small-molecule inhibitors of IL-2/IL-2R: lessons learned and applied.- Small Molecule Inhibitors of the Human Papillomavirus E1-E2 Interaction.- Design of small-molecule Smac mimetics as IAP antagonists.- Small-molecule inhibitors reveal a new function for Bcl-2 as a pro-angiogenic signaling molecule.- Small-molecule modulators of c-Myc/Max and Max/Max interactions.-  Small-molecule inhibitors of the p53-MDM2 interaction.- Subject index

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