Silencing, Heterochromatin and DNA Double Strand Break Repair

Author:   Kevin D. Mills
Publisher:   Springer
Edition:   2001 ed.
ISBN:  

9780792379829


Pages:   122
Publication Date:   31 October 2000
Format:   Hardback
Availability:   Out of print, replaced by POD   Availability explained
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Silencing, Heterochromatin and DNA Double Strand Break Repair


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Overview

This book concerns the origin, evolution, distribution, and destiny of life in the universe. It discusses the transition from inert matter to cellular life and its evolution to fully developed intelligent beings, and also the possibility of life occurring elsewhere, particularly in other environments in our own and other solar systems. The theoretical framework of astrobiology may be probed with a forthcoming series of space missions, which at the time of writing are being planned for the next 10 to 15 years. Advanced extraterrestrial life can also be probed by means of radioastronomy in the well-established project of search for extraterrestrial intelligence. Astrobiology pays special attention to the robust growth in our capacity to search for microorganisms, as well as signals of extraterrestrial life, with recent significant technological progress in planetary science and radioastronomy. The progress of the main space agencies is highlighted.

Full Product Details

Author:   Kevin D. Mills
Publisher:   Springer
Imprint:   Springer
Edition:   2001 ed.
Dimensions:   Width: 15.50cm , Height: 0.90cm , Length: 23.50cm
Weight:   0.830kg
ISBN:  

9780792379829


ISBN 10:   0792379829
Pages:   122
Publication Date:   31 October 2000
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of print, replaced by POD   Availability explained
We will order this item for you from a manufatured on demand supplier.

Table of Contents

1 Introduction to silencing, heterochromatin, and DNA break repair.- Yeast Silencing.- DNA Damage Repair.- Recent Findings.- 2 Identification and characterization of high-copy antagonists of silencing in Saccharomyces cerevisiae.- Results.- Discussion.- 3 MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double strand breaks.- Summary.- Results.- Discussion.- 4 The antisilencing gene ASF1 is required for resistance to DNA damage.- Results.- Discussion.- 5 Summary and Conclusions.- Summary.- DNA repair.- Role of SIR complex.- Role of ASF1.- Model for heterochromatin response.- Implications and questions.- Appendix A: Procedures.- Appendix B: Yeast strains.- Appendix C: Oligonucleotides.- References.

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