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Author:   Michael J Waring (University of Cambridge, UK) ,  Stephen Neidle ,  Dinshaw Patel ,  K. R. Fox
Publisher:   Royal Society of Chemistry
Imprint:   Royal Society of Chemistry
Volume:   Volume 6
Dimensions:   Width: 15.60cm , Height: 2.10cm , Length: 23.40cm
Weight:   0.560kg
ISBN:  

9780854043705

ISBN 10:   0854043705
Pages:   528
Publication Date:   15 September 2006
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Chapter 1: DNA recognition by triple helix formation; Chapter 2: Interfacial inhibitors of human topoisomerase I; Chapter 3: Diversity of topoisomerase I inhibitors for cancer chemotherapy; Chapter 4: Slow DNA binding; Chapter 5: DNA Gene Targeting using Peptide Nucleic Acid (PNA); Chapter 6: Actinomycin D - Sixty years of progress in characterising a sequence-selective DNA binding agent; Chapter 7: Thermal denaturation of drug-DNA complexes - Tools and tricks; Chapter 8: Computer simulations of drug-DNA interactions - a personal journey; Chapter 9: The discovery of G-quadruplex telomere targeting drugs; Chapter 10: The Mechanism of Action of Telomestatin, a G-Quadruplex-Interactive Compound; Chapter 11: Riboswitches and Ribozymes

Reviews

An excellent overview of the work being done in the exciting areas of discovering agents that exhibit selectivity and sequence specificity for DNA. Michael J Waring, who has been a pioneer in and made seminal contributions to this particular field. A comprehensive reference on this rapidly expanding field...is a must read...an excellent text book for a graduate course on this subject and a useful guide at the post-graduate level for biochemists as well as biophysicists. -- ChemBioChem, 2007, 8, 459-460 (Fu-Mling Chen) ChemBioChem

An excellent overview of the work being done in the exciting areas of discovering agents that exhibit selectivity and sequence specificity for DNA.Michael J Waring, who has been a pioneer in and made seminal contributions to this particular field.A comprehensive reference on this rapidly expanding field.....is a must read.....an excellent text book for a graduate course on this subject and a useful guide at the post-graduate level for biochemists as well as biophysicists. * ChemBioChem, 2007, 8, 459-460 (Fu-Mling Chen) *

An excellent overview of the work being done in the exciting areas of discovering agents that exhibit selectivity and sequence specificity for DNA. Michael J Waring, who has been a pioneer in and made seminal contributions to this particular field. A comprehensive reference on this rapidly expanding field...is a must read...an excellent text book for a graduate course on this subject and a useful guide at the post-graduate level for biochemists as well as biophysicists. -- ChemBioChem, 2007, 8, 459-460 (Fu-Mling Chen) ChemBioChem An excellent overview of the work being done in the exciting areas of discovering agents that exhibit selectivity and sequence specificity for DNA. Michael J Waring, who has been a pioneer in and made seminal contributions to this particular field. A comprehensive reference on this rapidly expanding field...is a must read...an excellent text book for a graduate course on this subject and a useful guide at the post-graduate level for biochemists as well as biophysicists.

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