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Author:   Michael S. Rosenberg
Publisher:   University of California Press
Imprint:   University of California Press
Dimensions:   Width: 15.20cm , Height: 2.50cm , Length: 22.90cm
Weight:   0.467kg
ISBN:  

9780520271319

ISBN 10:   0520271319
Pages:   360
Publication Date:   22 August 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Contributors Preface 1. Sequence Alignment: Concepts and History 2. Insertion and Deletion Events, Their Molecular Mechanisms, and Their Impact on Sequence Alignments 3. Local versus Global Alignments 4. Computing Multiple Sequence Alignment with Template-Based Methods 5. Sequence Evolution Models for Simultaneous Alignment and Phylogeny Reconstruction 6. Phylogenetic Hypotheses and the Utility of Multiple Sequence Alignment 7. Structural and Evolutionary Considerations for Multiple Sequence Alignment of RNA, and the Challenges for Algorithms That Ignore Them 8. Constructing Alignment Benchmarks 9. Simulation Approaches to Evaluating Alignment Error and Methods for Comparing Alternate Alignments Contents 10. Robust Inferences from Ambiguous Alignments 11. Strategies for Efficient Exploitation of the Informational Content of Protein Multiple Alignments References Index

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Author Information

Michael S. Rosenberg is Associate Professor of Computational Evolutionary Biology and Bioinformatics in the School of Life Sciences and the Center for Evolutionary Functional Genomics of the Biodesign Institute at Arizona State University.

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