Overview

Addressing the molecular mechanisms by which contraction of heart and skeletal muscles is regulated, this text also covers the modulation of these mechanisms by important (patho)physiological variables such as ionic composition of the myoplasm and phosphorylations of contractile and regulatory proteins. For the novice, this volume includes chapters that summarize current understanding of excitation-contraction coupling in striated muscles at the beginning of the 21st century, as well as the compositions and structures myofibrillar thick and thin filaments. For the expert, this volume presents detailed pictures of current understanding of the mechanisms underlying the CA2+ regulation of contraction in heart and skeletal muscles in 2002 and discusses important directions for future investigation.

Full Product Details

Author:   Simon C. Gandevia ,  Uwe Proske ,  Douglas G. Stuart
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   2002 ed.
Volume:   508
Dimensions:   Width: 17.80cm , Height: 3.10cm , Length: 25.40cm
Weight:   2.080kg
ISBN:  

9780306472855

ISBN 10:   0306472856
Pages:   518
Publication Date:   31 July 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of print, replaced by POD  
We will order this item for you from a manufatured on demand supplier.

Table of Contents

Section I: Impulse Initiation and Central Transmission from Muscle and Skin.- 1. Signalling Properties of Muscle Spindles and Tendon Organs.- 2. Evidence for Activity-Dependent Modulation of Sensory-Terminal Excitability in Spindles by Glutamate Release from Synaptic-Like Vesicles.- 3. Electrophysiology of Corneal Cold Receptor Nerve Terminals.- 4. Discharge Properties of Group III and IV Muscle Afferents.- 5. Effects of Activity on Axonal Excitability: Implications for Motor Control Studies.- 6. Reflexes in the Hand: Strong Synaptic Coupling Between Single Tactile Afferents and Spinal Motoneurones.- 7. The Synaptic Linkage for Tactile and Kinaesthetic Inputs to the Dorsal Column Nuclei.- Section II: Proprioception in Limb Movements.- 8. Proprioception: Peripheral Inputs and Perceptual Interactions.- 9. Adaptation to Coriolis Force Perturbation of Movement Trajectory: Role of Proprioceptive and Cutaneous Somatosensory Feedback.- 10. Velocity Perception and Proprioception.- 11. The Effect of Muscle Contraction on Kinaesthesia.- 12. Proprioception and Joint Pathology.- Section III: Afferent Contributions to Balance and Posture.- 13. Consequences and Assessment of Human Vestibular Failure: Implications for Postural Control.- 14. The Role of Cutaneous Receptors in the Foot.- 15. What does Galvanic Vestibular Stimulation Stimulate?.- 16. Sensory Interactions for Human Balance Control Revealed by Galvanic Vestibular Stimulation.- 17. Vestibulospinal Control of Posture.- 18. Sensory Contributions to the Control of Stance: A Posture Control Model.- Section IV: Motoneurones and Motor Units.- 19. Selectivity of the Central Control of Sensory Information in the Mammalian Spinal Cord.- 20. Some Unresolved Issues in Motor Unit Research.- 21. Presynaptic and Disynaptic Inhibition Induced by Group I Muscle Afferents.- 22. Things We Know and Do Not Know about Motoneurones.- 23. A New Way of Using Modelling to Estimate the Size of a Motoneuron’s EPSP.- 24. What Can Be Learned about Motoneurone Properties from Studying Firing Patterns?.- 25. Relative Strengths and Distributions of Different Sources of Synaptic Input to the Motoneurone Pool: Implications for Motor Unit Recruitment.- 26. Plateau Potentials and Their Role in Regulating Motoneuronal Firing.- 27. Mechanisms Causing Plateau Potentials in Spinal Motoneurones.- 28. Recent Evidence for Plateau Potentials in Human Motoneurones.- 29. Patterns of Pathological Firing in Human Motor Units.- Section V: Propriospinal Neurones and Spinal Reflexes.- 30. Reflections on Spinal Reflexes.- 31. Spinal Intemeurones: Re-evaluation and Controversy.- 32. Functional Properties of Primate Spinal Intemeurones during Voluntary Hand Movements.- 33. A Cervical Propriospinal System in Man.- 34. Premotoneuronal and Direct Corticomotoneuronal Control in the Cat and Macaque Monkey.- 35. Interspecies Comparisons for the C3-C4 Propriospinal System: Unresolved Issues.- 36. Central Nervous System Lesions and Segmental Activity.- 37. Reflex Mechanisms for Motor Impairment in Spinal Cord Injury.- Section VI: Locomotion.- 38. Give Proprioceptors a Chance.- 39. Role of the Fusimotor System in Locomotion.- 40. The Role of Proprioceptive Feedback in the Regulation and Adaptation of Locomotor Activity.- 41. Sensory Control of Locomotion: Reflexes versus Higher-Level Control.- 42. Reflex Excitation of Muscles during Human Walking.- 43. H Reflexes Recorded during Locomotion.- Section VII: Supraspinal Control of Movement.- 44. fMRI Studies of the Sensory and Motor Areas Involved in Movement.- 45. Dynamic Use of Tactile AfferentSignals in Control of Dexterous Manipulation.- 46. Motor Cortex and the Distributed Anatomy of Finger Movements.- 47. Reward-Based Planning of Motor Selection in the Rostral Cingulate Motor Area.- 48. Functional Differences in Corticospinal Projections from Macaque Primary Motor Cortex and Supplementary Motor Area.- 49. Corticospinal Transmission After Voluntary Contractions.- 50. Afferent and Cortical Control of Human Masticatory Muscles.- 51. Mechanisms for Acute Changes in Sensory Maps.- 52. Vision as Motivation: Interhemispheric Oscillation Alters Perception.- Section VIII: Mechanics and Movement.- 53. Musculoskeletal Mechanics: A Foundation of Motor Physiology.- 54. The Importance of Biomechanics.- 55. The Role of the Length-Tension Curve in the Control of Movement.- 56. Intramuscular Force Transmission.- 57. Muscle and Tendon Relations in Humans: Power Enhancement in Counter-Movement Exercise.- 58. Relationship Between Neural Drive and Mechanical Effect in the Respiratory System.

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