Overview

In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.

Full Product Details

Author:   Thomas J. Webster
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2009
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   0.547kg
ISBN:  

9780387786070

ISBN 10:   0387786074
Pages:   239
Publication Date:   02 December 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Developing Practices for Safe Handling of Nanoparticles and Nanomaterials in a Development-Stage Enterprise: A Practical Guide for Research and Development Organizations.- Cytotoxicity of Photoactive Nanoparticles.- Breeching Epithelial Barriers – Physiochemical Factors Impacting Nanomaterial Translocation and Toxicity.- Safety and Efficacy of Nano/Micro Materials.- Biomedical Applications of Nanoparticles.- Unexpected Reactions by In Vivo Applications of PEGylated Liposomes.- Hydrogel Nanocomposites: Biomedical Applications, Biocompatibility, and Toxicity Analysis.- Cytotoxicity and Genotoxicity of Carbon Nanomaterials.- Calcium Phosphate Nanoparticles: Toxicology and Lymph Node Targeting for Cancer Metastasis Prevention.- Nanoparticles for Cancer Diagnosis and Therapy.

Reviews

From the reviews: This book provides an interdisciplinary background, a valuable reference source, and a concise summary of the state of the art of various aspects of the field! While collectively covering some of the broad issues, each article provides details of specific nanoparticles, interactions, or applications. -- Hugh J. Byrne, Analytical and Bioanalytical Chemistry, September, 2009

"From the reviews: ""This book provides an interdisciplinary background, a valuable reference source, and a concise summary of the state of the art of various aspects of the field… While collectively covering some of the broad issues, each article provides details of specific nanoparticles, interactions, or applications.""  – Hugh J. Byrne, Analytical and Bioanalytical Chemistry, September, 2009"

From the reviews: This book provides an interdisciplinary background, a valuable reference source, and a concise summary of the state of the art of various aspects of the field... While collectively covering some of the broad issues, each article provides details of specific nanoparticles, interactions, or applications. - Hugh J. Byrne, Analytical and Bioanalytical Chemistry, September, 2009

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