Role of the Choroid Plexus in Health and Disease

Author:   Jeppe Praetorius ,  Bonnie Blazer-Yost ,  Helle Damkier
Publisher:   Springer-Verlag New York Inc.
Edition:   1st ed. 2020
ISBN:  

9781071605387


Pages:   287
Publication Date:   18 April 2021
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Role of the Choroid Plexus in Health and Disease


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This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF). The authors show that this barrier is crucial for maintaining important compositional differences between the blood plasma and the CSF. The choroid plexus epithelial cells also prevent the spread of infectious agents and other blood-borne entities to the brain tissue.  Chapter topics range from the production of CSF by electrolyte regulation in the choroid plexus, to details on the selectively transporting nature of this barrier. Further, the authors elaborate on the important roles of CSF in sustaining brain health by providing hydration, solutes, and nutrients to the brain tissue. Readers will also learn how CSF circulates signaling molecules within the compartments of the brain and removes waste products from the brain tissue. Elucidating the regulation of these processes in thechoroid plexus is not only important for the readers’ understanding of normal brain development and function, but is also crucial for resolving a variety of cerebral challenges that lead to brain edema, as well as developing treatments for diseases. The book discusses disease models like hydrocephalus, sleep disorders, and age-related dementia. Its comprehensive coverage makes this volume a valuable resource for researchers in cell and neurophysiology, as well as graduate students of the neurosciences.

Full Product Details

Author:   Jeppe Praetorius ,  Bonnie Blazer-Yost ,  Helle Damkier
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   1st ed. 2020
Weight:   0.456kg
ISBN:  

9781071605387


ISBN 10:   1071605380
Pages:   287
Publication Date:   18 April 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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Jeppe Praetorius Department of Biomedicine Aarhus University Aarhus Denmark Bonnie Blazer-Yost Department of Biology Indiana University – Purdue University Indianapolis Indianapolis Indiana USA Helle Damkier Department of Biomedicine Aarhus University Aarhus Denmark

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