Overview

This book looks at the role of proteases, which are enzymes that digest proteins, and the various roles that proteases play in the development of neurodegenerative diseases such as Alzheimer's disease, ALS, epilepsy, multiple sclerosis, as well as numerous other neuromuscular diseases.

Full Product Details

Author:   Abel Lajtha ,  Naren L. Banik
Publisher:   Springer Science+Business Media
Imprint:   Plenum Publishing Co.,N.Y.
Edition:   2001 ed.
Dimensions:   Width: 17.80cm , Height: 1.90cm , Length: 25.40cm
Weight:   1.840kg
ISBN:  

9780306465796

ISBN 10:   0306465795
Pages:   302
Publication Date:   31 July 2001
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1. The Role of Proteolytic Enzymes in Autoimmune Demyelinating Diseases: An Update; M.E. Smith. 2. Proteases in Demyelination; M.L. Cuzner. 3. Calcium Activated Neutral Proteinase in Demyelinating Diseases; D.C. Shields, N.L. Banik. 4. Papain-Like Cysteine Proteases and Their Implications in Neurodegenerative Diseases; D. Broeme, S. Petanceska. 5. The Role of the Calpain System in Neuromuscular Disease; D.E. Goll, et al. 6. The Role of Calpain Proteolysis in Cerebral Ischemia; D.F. Emerich, R.T. Bartus. 7. Calpain Isoforms in the Eye; T.R. Shearer, et al. 8. Metalloendopeptidase EC 3.4.24.15 in Neurodegeneration; C.R. Abraham, F. Slot. 9. Cysteine Proteases, Synaptic Degeneration and Neurodegenerative Disorders; M.P. Mattson, S.L. Chan. 10. The Ubiquitin/Proteasome Pathway in Neurological Disorders; M.E. Figueiredo-Pereira, P. Rockwell. 11. Amyloid (Tace, Bace) and Presenilin Proteases Associated with Alzheimer's Disease; N. Marks, M.J. Berg. 12. Caspases in Neurodegeneration; J. Schulz, M. Moskowitz. 13. Therapeutic Approaches with Protease Inhibitors in Neurodegenerative and Neurological Diseases; K.K.W. Wang. 14. Pathophysiology of Central Nervous System Trauma: Proteolytic Mechanisms and the Related Therapeutic Approaches; S.K. Ray, et al. 15. Lysosomal Cysteine Proteases and Their Protein Inhibitors; V. Turk, et al. 16. Proteases and Their Inhibitors in Gliomas; P.A. Forsyth, et al. 17. Proteolysis of Mutant Gene Products are Key Mechanisms inNeurodegenerative Diseases; V.Y.H. Hook. 18. Mammalian Proteinase Genes; H.-J. Lee, et al.

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Author Information

Dr. Lajtha is the editor of the Journal of Neurochemical Research.

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