Overview

Nitric oxide (NO), an endogenous free radical, has been shown recently to mediate several important biological effects. It plays a neurotransmitter-like role in vascular endothelium, a second-messenger role in N-methyl-D-aspartate (NMDA) responsive neurons in the central nervous system (CNS), a neurotoxic role after its release from these neurons, and a cytotoxic role after its release by macrophages. This volume reviews the basic chemistry and physical properties of S-nitrosothiols (RS-NO) and their biochemical mechanisms of action, NO synthase isozymes, NO synthase structure, mechanisms of NO synthesis, regulation of NO expression and post-translational modification, and mechanisms involving NO of central nervous system damage in virus infections.

Full Product Details

Author:   Hilary Koprowski ,  Hiroshi Maeda
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Volume:   v.196
Weight:   0.295kg
ISBN:  

9783540582144

ISBN 10:   3540582142
Pages:   99
Publication Date:   16 May 1995
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

List of Contents.- Inducible Nitric Oxide Synthase: Regulation Subserves Function.- Diffusible Messengers and Intercellular Signaling: Locally Distributed Synaptic Potentiation in the Hippocampus.- Nitric Oxide Formation in the Vascular Wall: Regulation and Functional Implications.- S-Nitrosothiols and the Bioregulatory Actions of Nitrogen Oxides Through Reactions with Thiol Groups.- A New Nitric Oxide Scavenger, Imidazolineoxyl N-Oxide Derivative, and Its Effects in Pathophysiology and Microbiology.- The Role of Nitric Oxide in the Pathogenesis of Virus-Induced Encephalopathies.- The Role of Peroxynitrite in Nitric Oxide-Mediated Toxicity.- Regulation and Dysregulation of Constitutive Nitric Oxide Synthases Types I and III.

Reviews

""In the past six years, the field of nitric oxide research has undergone explosive growth... This volume can be taken as a short introduction to the field of nitric oxide research. For the advanced student or the scientist who wants a quick impression of major aspects of this field it may be a good introduction ..."" Journal of Chemical Neuroanatomy

In the past six years, the field of nitric oxide research has undergone explosive growth.... This volume can be taken as a short introduction to the field of nitric oxide research. For the advanced student or the scientist who wants a quick impression of major aspects of this field it may be a good introduction .... Journal of Chemical Neuroanatomy

In the past six years, the field of nitric oxide research has undergone explosive growth... This volume can be taken as a short introduction to the field of nitric oxide research. For the advanced student or the scientist who wants a quick impression of major aspects of this field it may be a good introduction ... Journal of Chemical Neuroanatomy

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions