Overview

Risk Factors for Cerebrovascular Disease and Stroke address the relationship of a wide variety of vascular risk factors in the spectrum of cerebrovascular diseases. An international group of professionals the forefront of research and education, provide their expertise about environmental and genetic determinants for cerebrovascular disease and stroke. The authors aim to provide information on developments of genetic, environmental and lifestyle-related risk factors of various subtypes of stroke, and MRI-markers of cerebrovascular disease.One in two men, and one in three women after the age of 40, will develop a stroke in their lifetime. The burden of cerebrovascular disease extends far beyond that of acute clinical events such as stroke, with ""covert"" vascular injury on brain MRI being highly prevalent in older community-dwelling persons. Therefore, improving our understanding of the risk factors for stroke and cerebrovascular disease is of paramount importance for improving prevention strategies. Secular trends in stroke epidemiology, risk factors, and intermediate markers (including carotid ultrasound, brain MRI and circulating biomarkers) are presented. Cutting edge information on genetic, environmental and lifestyle-related risk factors of various subtypes of stroke and MRI-markers of cerebrovascular diseases are displayed. This important book is an essential reference to physicians interested in more effective primary prevention of stroke.

Full Product Details

Author:   Sudha Seshadri (MD, DM, MD, DM, Department of Neurology and Inserm Center U897, Epidemiology; Bordeaux University Hopsital and University of Bordeaux, Bordeaux, France) ,  Stéphanie Debette (MD, PhD, MD, PhD, L'Universiti Paris Est, Paris, France)
Publisher:   Oxford University Press Inc
Imprint:   Oxford University Press Inc
Dimensions:   Width: 23.60cm , Height: 3.10cm , Length: 16.00cm
Weight:   0.816kg
ISBN:  

9780199895847

ISBN 10:   0199895848
Pages:   488
Publication Date:   21 April 2016
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

I. Introduction 1. Epidemiology of stroke: incidence and prevalence, description of types and subtypes and their relative frequency, definition of risk factors II. Genetic risk factors 2. Introduction to Genetic risk factors for cerebrovascular disease 3. Monogenic forms of stroke and cerebrovascular disease 4. Heritability of stroke 5. Genetic determinants of ischemic stroke discovered through GWAS 6. Genetic risk factors of intracerebral haemorrhage 7. Relevance in stroke of genes associated with cardiovascular disease and risk factors\ 8. Genetics of Stroke associated with cervical artery dissections 9. Genetics of cerebral venous thrombosis 10. Genetic risk factors for brain MRI markers of cerebrovascular disease III. Environmental risk factors 11. Overview of Environmental Risk Factors for Stroke 12. Hypertension: the major risk factor for stroke 13. Dyslipidemia and Risk of Stroke 14. Metabolic risk factors: DM, obesity, metabolic syndrome 15. Lifestyle factors and Risk of Stroke: smoking, alcohol, diet, physical activity, sleep 16. Risk factors specific to young adults 17. Sex-Specific Risk factors for Stroke in Women 18. Migraine and Risk of Stroke and Cerebrovascular Disease 19. Ethnic, Racial and Geographic Variations in Stroke Risk and Risk Factors IV. Integrative approach 20. Intermediate markers: Carotid Atherosclerosis 21. MRI-based Markers of Cerebrovascular Disease and the Risk of Stroke 22. Circulating Biomarkers for Stroke 23. Secular trends in Stroke Risk and Risk factors for Stroke

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Author Information

Sudha Seshadri, MD Department of Neurology Boston University School of Medicine Investigator, The Framingham Heart Study Boston, MA Stéphanie Debette, MD, PhD Department of Neurology and Epidemiology Paris Diderot University Paris, France

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