Ring Nitrogen and Key Biomolecules: The Biochemistry of N-Heterocycles

Author:   E.G. Brown
Publisher:   Chapman and Hall
Edition:   1998 ed.
ISBN:  

9780412835704


Pages:   242
Publication Date:   31 July 1998
Format:   Hardback
Availability:   In Print   Availability explained
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Ring Nitrogen and Key Biomolecules: The Biochemistry of N-Heterocycles


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Author:   E.G. Brown
Publisher:   Chapman and Hall
Imprint:   Chapman and Hall
Edition:   1998 ed.
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   1.200kg
ISBN:  

9780412835704


ISBN 10:   0412835703
Pages:   242
Publication Date:   31 July 1998
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

1. Pyrroles and tetrapyrroles, including porphyrins.- 1.1 Introduction.- 1.2 Natural occurrence of monopyrroles.- 1.3 Pyrrolic properties of biochemical relevance.- 1.4 Discovery and natural occurrence of tetrapyrroles and related compounds.- 1.5 Natural occurrence of dipyrroles and tripyrroles.- 1.6 Porphyrin biosynthesis and interconversion.- 1.7 Porphyrin catabolism and the formation of bile pigments and phycobilins.- 1.8 Biochemical functions.- 1.9 Biological and pharmacological activity.- 1.10 Synthetic compounds of clinical importance.- References.- Wider Reading (books and reviews).- 2. Imidazoles and benzimidazoles.- 2.1 Discovery and natural occurrence.- 2.2 Chemical properties of biochemical interest.- 2.3 Biosynthesis.- 2.4 Catabolism.- 2.5 Biological functions.- 2.6 Biological and pharmacological activity.- References.- Wider Reading.- 3. Pyrazoles.- 3.1 Discovery and natural occurrence.- 3.2 Chemical properties of biochemical interest.- 3.3 Biosynthesis of pyrazole and ?-pyrazol-1-ylalanine.- 3.4 Catabolism.- 3.5 Biological and pharmacological activity.- 3.6 Synthetic pyrazoles of medical and agricultural importance.- References.- 4. Pyridines.- 4.1 Discovery and natural occurrence.- 4.2 Chemical properties of biochemical interest.- 4.3 Biosynthesis and interconversion.- 4.4 Catabolism.- 4.5 Biochemical functions.- 4.6 Biological and pharmacological activity of pyridine derivatives.- 4.7 Synthetic compounds of clinical importance.- 4.8 Compounds of agricultural importance.- References.- Wider Reading (books and reviews).- 5. Pyrimidines.- 5.1 Discovery and occurrence.- 5.2 Chemical properties of biochemical interest.- 5.3 Biosynthesis and interconversion.- 5.4 Pyrimidine catabolism.- 5.5 Biochemical functions of pyrimidines.- 5.6 Biological andpharmacological activity of naturally occurring pyrimidines.- 5.7 Synthetic pyrimidines of pharmaceutical interest.- 5.8 Pyrimidines in horticultural and agricultural use.- 5.9 Pyrimidine chemistry and biochemistry, conclusions.- References.- Wider Reading (books and reviews).- 6. Purines.- 6.1 Discovery and natural occurrence.- 6.2 Chemical properties of biological significance.- 6.3 Biosynthesis and interconversion.- 6.4 Purine catabolism.- 6.5 Defects in purine metabolism.- 6.6 Biochemical functions of purines.- 6.7 Biological and pharmacological activity.- 6.8 Synthetic purines and purine analogues of clinical importance.- 6.9 Conclusions.- References.- Wider Reading (books and reviews).- 7. Pteridines.- 7.1 Discovery and natural occurrence.- 7.2 Chemical and physical properties of biochemical interest.- 7.3 Biosynthesis of folates.- 7.4 Catabolism.- 7.5 Biochemical role of folic acid and its derivatives.- 7.6 Synthetic compounds of clinical importance.- References.- Wider Reading (books and reviews).- 8. Flavins.- 8.1 Discovery and natural occurrence.- 8.2 Chemical properties of biochemical interest.- 8.3 Biogenesis of flavins and pteridines.- 8.3 Biosynthesis of riboflavin.- 8.4 Biochemical role of riboflavin and its derivatives.- 8.5 Synthetic compounds of medicinal or agricultural interest.- References.- Wider Reading (books and reviews).- 9. Indoles.- 9.1 Discovery and natural occurrence.- 9.2 Chemical properties of biochemical interest.- 9.3 Biosynthesis and interconversion.- 9.4 Catabolism.- 9.5 Biochemical functions.- 9.6 Biological and pharmacological activity.- 9.7 Synthetic compounds of clinical importance.- 9.8 Compounds of agricultural and horticultural importance.- Wider Reading (books and reviews).- 10. N-Heterocycles and living systems —conclusions.

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