Rho Family GTPases
Author:   Edward J. Manser
Publisher:   Springer-Verlag New York Inc.
Edition:   2005 ed.
Volume:   3
ISBN:  

9781402034619


Pages:   298
Publication Date:   24 June 2005
Format:   Hardback
Availability:   In Print   Availability explained
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Rho Family GTPases


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Overview

Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted. The book includes an overview of how Rho GTPases become activated which is complemented by an extensive Chapter by Darerca Owen and Helen Mott who unravel the beautiful molecular details given to us by the many structural studies of Rho GTPases. The key areas currently being investigated in relation to these ubiquitous proteins are described for both in vitro and in vivo systems. These are presented in a format that ensures the reader can approach the topic with minimal background knowledge, while ultimately bringing the subject to the level of an expert. Timely and highly authoritative, this volume illuminates newer findings, particularly as they relate to Rho proteins in vertebrate biology.

Full Product Details

Author:   Edward J. Manser
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2005 ed.
Volume:   3
Dimensions:   Width: 15.60cm , Height: 1.90cm , Length: 23.20cm
Weight:   1.360kg
ISBN:  

9781402034619


ISBN 10:   140203461
Pages:   298
Publication Date:   24 June 2005
Audience:   College/higher education ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

The Rho GTPases.- Evolution of the Human Rho GTPase Family.- Structural Analysis of Rho Protein Complexes.- Activation of GTPases by Dock180 Family of Proteins.- Rho GAPs — Regulators of Rho GTPases and More.- RhoA/C and the Actin Cytoskeleton.- Cdc42 and Rac Control of the Actin Cytoskeleton.- Regulation of Cell-Cell Adhesion by Rho Family GTPases.- Rho Proteins and Vesicle Trafficking.- The Prototype Rho-Associated Kinase PAK.- Genetic Analysis of Rho Protein Function in Mice.- Rho Proteins and Microtubules.

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