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OverviewThis book features papers presented at a workshop discussing current knowledge about the biological effects of low level exposures (BELLE). The book is designed to help establish a scientific base for future BELLE initiatives and is focused on the issue of the toxicological implications of biological adaptations. Hormesis is considered in a broad, conceptual manner, as well as at molecular and biochemical levels. Other topics covered include the effects of low levels of radiation on biological systems, how the liver adapts to genetic insults, biostatistical considerations when designing studies that address issues associated with biological responses to low doses of chemicals and radiation, and the issues that surround the interpretation of findings from such studies. Full Product DetailsAuthor: Edward J. Calabrese (University of Massachusetts, Amherst, USA)Publisher: Taylor & Francis Ltd Imprint: CRC Press Weight: 0.453kg ISBN: 9781138557741ISBN 10: 1138557749 Pages: 172 Publication Date: 28 January 2019 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1.Hypotheses on Mammalian Aging, Toxicity, and Longevity Hormones 2. The Role of the ‘Stress Protein Response’ in Hormesis 3. DNA Repair 4. Biochemical Mechanisms of Biphasic Dose-Response Relationships 5. Effects of Low-Dose Radiation on the Immune Reponse 6. Cellular Adaption as an Important Response During Chemical Carcinogenesis 7. Bio statistical Approaches for Modelling U-shaped Dose-Response Curves and Study Design Considerations in Assessing the Biological Effects of Low DosesReviewsAuthor InformationEdward J. Calabrese is an American toxicologist and professor in the department of environmental health sciences at the University of Massachusetts Amherst. He is the editor-in-chief of the scientific journal Dose-Response. Tab Content 6Author Website:Countries AvailableAll regions |
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