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OverviewThis critical, state-of-the-art review brings together the scattered and often controversial information on multidrug resistance reversal. Leading scientists in the field cover P-glycoprotein, the genetics of resistance, and its reversal by drugs. Resistance modifiers and modulators are tabulated and critically evaluated. Reversal of Multidrug Resistance in Cancer is important reading for oncologists, cancer chemotherapists, and other cancer researchers. Full Product DetailsAuthor: John A. Kellen (Toronto, ON, Canada) , Catherine A. O'Brian (University of Texas, Houston, USA) , June L. Biedler , Dominic FanPublisher: Taylor & Francis Inc Imprint: CRC Press Inc Dimensions: Width: 15.60cm , Height: 1.60cm , Length: 23.40cm Weight: 0.426kg ISBN: 9780849347443ISBN 10: 0849347440 Pages: 160 Publication Date: 06 December 1993 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Out of Print Availability: Out of stock ![]() Table of ContentsPreface (J.A. Kellen). The Phenomenon of Multidrug Resistance (J.A. Kellen). Collateral Sensitization in Multidrug Resistance (J.L. Biedler and B.A. Spengler). Cytogenetics of Multidrug Resistance (R. Ganapathi, D. Grabowski, and G. Hoeltge). Mathematical Models of Multidrug Resistance (J. Goldie, A.J. Coldman, and A. Lai). Multidrug Resistance in Human Malignancies (J.A. Kellen). Reversal of Multidrug Resistance (D. Fan, P.J. Beltran, and C.A. O'Brian). Outlook (J.A. Kellen and D. Fan). Conclusion (J.A. Kellen). Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |