Resistance to Immunotoxins in Cancer Therapy

Author:   Rama Shanker Verma ,  Benjamin Bonavida
Publisher:   Springer International Publishing AG
Edition:   2015 ed.
Volume:   6
ISBN:  

9783319172743


Pages:   249
Publication Date:   27 June 2015
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Resistance to Immunotoxins in Cancer Therapy


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Author:   Rama Shanker Verma ,  Benjamin Bonavida
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   2015 ed.
Volume:   6
Dimensions:   Width: 15.50cm , Height: 1.60cm , Length: 23.50cm
Weight:   5.266kg
ISBN:  

9783319172743


ISBN 10:   3319172743
Pages:   249
Publication Date:   27 June 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Targeted Cancer Therapy: History and Development of Immunotoxins.-2 Immunotoxins, Resistance and Cancer Stem Cells: Future Perspective.-3 Factors that Determine Sensitivity and Resistances of Tumor Cells Towards Antibody-Targeted Protein Toxins.-4 Cell Signaling and Resistance to Immunotoxins.-5 Antibody-Drug Conjugates and Immunotoxins for the Treatment of Hematologic Neoplasms.-6 Challenges for Therapeutic Application of Pseudomonas Exotoxin-Based Immunotoxins .-7 Drug Resistance to Calicheamicin Conjugated Monoclonal Antibody Therapy .-8 Engineered Versions of Granzyme B and Angiogenin Overcome Intrinsic Resistance to Apoptosis Mediated by Human Cytolytic Fusion Proteins.-9 Therapeutic Impact of Immune Responses in Cancer.

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Author Information

Rama Shanker Verma, Ph.D., is Professor, Department of Biotechnology, the Indian Institute of Technology. Professor Verma specializes in the development of novel immunotoxins for cancer therapies. He has published 76 scientific articles, five book chapters, and several conference abstracts. He is an Elected Fellow, the Association of Microbiologists of India an Elected Fellow, the Society for Applied Biotechnology. He received the award for Excellence in Medical Biotechnology from the Society for Applied Biotechnology.

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