Overview

This book presents the latest advances in the field of regenerative medicine in plastic surgery. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner.The first part introduces readers to essential principles of skin and soft tissue regeneration, e.g. the possibility of using mesenchymal stem cells for wound healing. Since bone serves as a supportive tissue in most of the body, bone regeneration is an important aspect of regenerative medicine; accordingly, the second part discusses the novel bone implants, activated bone grafts and bone tissue engineering. The book’s third part, focusing on cartilage regeneration, includes chapters on e.g. stem cells and ear regeneration. In turn, part four addressesmuscle and tendon regeneration: from tendon to bone and tendon to muscle, as well as aging in the realm of muscle regeneration. Lastly, part five highlights nerve regeneration, deepening surgeons’ knowledge to help them successfully treat injuries to the peripheral neural system. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. ""With beautiful clinical images and artwork, this book will be a central companion to both practicing plastic surgeons who wish to remain abreast of oncoming technologic advances and regenerative medicine researchers who wish to understand the current state of the art of surgical reconstruction."" - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine

Full Product Details

Author:   Dominik Duscher ,  Melvin A. Shiffman
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2019
Weight:   1.493kg
ISBN:  

9783030199616

ISBN 10:   3030199614
Pages:   472
Publication Date:   13 December 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

PART 1: SKIN AND SOFT TISSUE REGENERATION1. Induction of the Fetal Scarless Phenotype in Adult Wounds: Impossible?2. Scar Treatment and Prevention: Know Thine Enemy3. Challenges and Opportunities in Drug Delivery and Wound Healing4. Harvesting, Processing and Injection of Lipoaspirate for Soft Tissue Reconstruction - Details Make the Difference5. Adipose Tissue Complex (ATC): Cellular & Biocellular Uses of Stem/Stromal Cells & Matrix in Cosmetic Plastic, Reconstructive Surgery & Regenerative Medicine6. Preparation, Characterization, and Clinical Implications of Human Decellularized Adipose Tissue Extracellular Matrix7. Mesenchymal Cells that Support Human Skin Regeneration8. Stem Cells and Burn9. Skin Tissue Engineering Advances in Severe Burns: Review and Therapeutic Applications10. Skin Substitutes for Burn Wounds11. Wnt Signaling During Cutaneous Wound Healing12. Drug Delivery Advances for the Regeneration of Aged SkinPART 2: BONE REGENERATION13. Innovative Scaffold Solution for Bone Regeneration Made of Beta-Tricalcium Phosphate Granules, Autologous Fibrin Fold and Peripheral Blood Stem Cells14. Ordinary and Activated Bone Substitutes15. Absorbable Bone Substitute Materials Based on Calcium Sulfate as Triggers for Osteoinduction and Osteoconduction16. Perivascular Progenitor Cells for Bone Regeneration17. Bone Repair and Regeneration is Regulated by the Wnt Signaling PathwayPART 3: CARTILAGE REGENERATION18. Cartilage Tissue Engineering: Role of Mesenchymal Stem Cells, Growth Factors and Scaffolds19. Sox9 Potentiates BMP2-induced Chondrogenic Differentiation and Inhibits BMP2-induced Osteogenic Differentiation20. Stem Cells and Ear RegenerationPART 4: MUSCLE AND TENDON REGENERATION21. Muscle Fiber Regeneration in Long Term Denervated Muscles. Basics and Clinical Perspectives22. Rejuvenating Stem Cells to Restore Muscle Regeneration in Aging23. Silk Fibroin-Decorin Engineered Biologics to Repair Musculofascial Defects24. Skeletal Muscle Restoration Following Volumetric Muscle Loss: the Therapeutic Effects of a Biologic Surgical Mesh25. Principles of Tendon Regeneration26. Stem Cells and Tendon Regeneration27. Cell Therapies for Tendon: Treatments and Regenerative MedicinePART 5: NERVE REGENERATION28. The present and future for peripheral nerve regeneration29. The Regeneration of Peripheral Nerves Depends on Repair Schwann Cells30. Adipose-derived Stem Cells (ASCs) for Peripheral Nerve Regeneration31. Direct Reprogramming Somatic Cells into Functional Neurons: A New Approach to Engineering Neural Tissue in Vitro and in Vivo

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Author Information

Dr. Dominik Duscher MD, PhD, is the director of the Division of Experimental Plastic Surgery at Technical University of Munich. He holds a doctorate of medicine and a research doctorate focusing on Stem Cell Biology and Regenerative Medicine. After his medical education in Vienna (Medical University of Vienna), London (University College London) and Boston (Harvard Medical School) he graduated from a postdoctoral fellowship in Stem Cell Biology and Regenerative Medicine at Stanford University. For his research he received the Stanford University biomaterial research prize, and scholarships from the American Austrian Foundation and the Austrian Science Fund, among other distinctions. Dr. Duscher holds multiple patents, published more than 100 peer reviewed publications and authored more than 100 conference presentations. Dominik Duscher is the General Secretary of the European Plastic Surgery Research Council. He further acts as the Research Coordinator of the MicrosurgicalEducation Center of the Kepler University Hospital Linz and the Young Forum of the Austrian Society for Surgery of the Hand. Dr. Melvin A. Shiffman, MD, JD, FCLM, received his MD from Northwestern University School of Medicine in 1957 and completed his residency in general surgery in 1964 at the Veterans Administration Hospital, Long Beach, California. Since then he has been continuously involved in oncologic surgery, reconstruction, and cosmetic surgery. In 2002, Dr. Shiffman became Chair of the Section of Surgery at Tustin Hospital and Medical Center and in 2009-10 he served as President of the American College of Legal Medicine. He is Editor Emeritus of the American Journal of Cosmetic Surgery, a member of the Scientific Committee of the American Journal of Aesthetic Medicine, and an examiner for the International Board of Cosmetic Surgery. He is also a former Editor-in-Chief of both the American Journal of Cosmetic Surgery and the InternationalJournal of Cosmetic Surgery. Dr. Shiffman is the recipient of many honors and is a fellow of various colleges and societies. He has published 320 articles, authored or edited 50 books, and written more than 210 book chapters.

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