Overview

The aim of this book is to cover the very recent developments in asymmetric organocatalysis, focussing on those published since the beginning of 2008. The last decade has witnessed an explosive growth in the field of asymmetric organocatalysis with an impressive amount of new catalysts, novel methodologies, and applications in numerous reaction types, such as nucleophilic substitutions, addition reactions, as well as cycloadditions, oxidations, reductions, kinetic resolutions, and miscellaneous reactions. This very diverse and intensely developing field is too wide to cover in a single review. The timeliness of the book together with the expected impact is excellent, since nowadays asymmetric organocatalysis is arguably the most intensively developed field in organic chemistry. The book is designed to meet the demands of a postgraduate textbook,containing case studies and Q&A sections, as well as a practical book filled with facts and data useful as a working tool for the practitioner. The book is divided into ten sections, dealing successively with nucleophilic additions to electron-deficient C=C double bonds, nucleophilic additions to C=O double bonds, nucleophilic additions to C=N double bonds, nucleophilic additions to unsaturated nitrogen, nucleophilic substitutions at aliphatic carbon, cycloaddition reactions, oxidations, reductions, kinetic resolutions and desymmetrisations, and miscellaneous reactions.

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9781849730549

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Reviews

A strength of the book lies in the extensive use of graphics. Virtually every entry in the book is provided a graphic summary of the best cases for a particular report. This compilation can be regarded as a snapshot of progress for a field that requires treatment in any modern graduate program in organic chemistry. ...the author has produced a work that is commendable by the measures of the topics selected and their organization. -- Journal of the American Chemical Society (JACS),2011, 133, 2330 - 2330, Jeffrey N Johnston Journal of the American Chemical Society (JACS) ...this book was set out to update the audience on the application of asymmetric organocatalysis after several earlier review articles and this certainly meets the task with a plethora of detailed reports on important asymetric organic catalysed processes. This book will appeal to those researchers engaged in catalysis at phD or post-doctoral level and provides a useful compendium on a wide number of organocatalytic transformations. -- Chemistry World, February 2011, Benjamin Buckley Chemistry World

<p>No Metals Please <p>Recent Developments in Asymmetric Organocatalysis<p>H l ne Pellissier<br>RSC Publishing, Cambridge, UK, 2010, 260pp (HB) ISBN 9781849730549<br><p> Reviewed by Benjamin Buckley <p>This book forms part of the RSC Catalysis series (Part 3) and deals with developments in organocatalysis from 2008 to early 2009. <p>Organocatalysis is a highly contemporary area of research in which asymmetric reactions are catalysed by organic molecules.<p>The author has divided the book into 10 chapters, each individually dealing with different types of organocatalytic reactions, for example, amongst others, nucleophilic addition to C=C, C=O and C=N bonds, cycloaddition, oxidation, and reduction reactions.<p>Perhaps one downfall of this approach is that it reads rather like a catalogue of reactions and it would have been nice to see mechanistic arguments and details on the origin of asymmetric induction in some reactions.<p>On balance this book was set out to update the audience one

<p>No Metals Please <p>Recent Developments in Asymmetric Organocatalysis<p>H l ne Pellissier<br>RSC Publishing, Cambridge, UK, 2010, 260pp (HB) ISBN 9781849730549<br><p> Reviewed by Benjamin Buckley <p>This book forms part of the RSC Catalysis series (Part 3) and deals with developments in organocatalysis from 2008 to early 2009. <p>Organocatalysis is a highly contemporary area of research in which asymmetric reactions are catalysed by organic molecules.<p>The author has divided the book into 10 chapters, each individually dealing with different types of organocatalytic reactions, for example, amongst others, nucleophilic addition to C=C, C=O and C=N bonds, cycloaddition, oxidation, and reduction reactions.<p>Perhaps one downfall of this approach is that it reads rather like a catalogue of reactions and it would have been nice to see mechanistic arguments and details on the origin of asymmetric induction in some reactions.<p>On balance this book was set out to update the audience ons

Author Information

Hélène Pellissier is at the CNRS, Marseille, France. She carried out her PhD under the supervision of Dr G Gil in Marseille and then joined the Centre National de la Recherche Scientifique in 1988. After a postdoctoral position in Professor KPC Vollhardt's group at Berkeley, she joined the group of Professor M Santelli in Marseille in 1992, where she focused on the chemistry of BISTRO and its large application in organic synthesis. There, she developed several new very short total syntheses of steroids starting with 1,3-butadiene and benzocyclobutenes.

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