Recent Advancement in Prodrugs
Author:   Kamal Shah ,  Durgesh Nandini Chauhan ,  Nagendra Singh Chauhan ,  Pradeep Mishra
Publisher:   Taylor & Francis Ltd
ISBN:  

9780367348366


Pages:   336
Publication Date:   28 May 2020
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Recent Advancement in Prodrugs


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Overview

Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.

Full Product Details

Author:   Kamal Shah ,  Durgesh Nandini Chauhan ,  Nagendra Singh Chauhan ,  Pradeep Mishra
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Weight:   0.453kg
ISBN:  

9780367348366


ISBN 10:   0367348365
Pages:   336
Publication Date:   28 May 2020
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Recent advancements in New drug design and development of prodrugs. Codrugs: Optimum use through prodrugs. Role of Prodrugs in Drug Design. Prodrugs for enhancement of lipophilicity. Lipidic Prodrugs for Drug Delivery: Opportunities and Challenges. The progress of prodrugs in drug solubility. Prodrugs for CNS drug delivery. Prodrugs for Cancer Treatment. Prodrugs in cancer nanomedicine and therapy. Nitroreductases in prodrug therapies. Prodrug approach using carboxylesterase: Different substrate specificities of human carboxylesterase isozymes. Mathematical models for ADME of prodrugs. Prodrug Approaches for Natural Products. Biotechnology based prodrug approach for cell-specific targeting: its theoretical basis and application.

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Kamal Shah, Durgesh Nandini Chauhan, Nagendra Singh Chauhan, Pradeep Mishra

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