Randomized Phase II Cancer Clinical Trials

Author:   Sin-Ho Jung
Publisher:   Taylor & Francis Ltd
ISBN:  

9780367576455


Pages:   244
Publication Date:   30 June 2020
Format:   Paperback
Availability:   In Print   Availability explained
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Randomized Phase II Cancer Clinical Trials


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Full Product Details

Author:   Sin-Ho Jung
Publisher:   Taylor & Francis Ltd
Imprint:   Chapman & Hall/CRC
Weight:   0.344kg
ISBN:  

9780367576455


ISBN 10:   0367576457
Pages:   244
Publication Date:   30 June 2020
Audience:   College/higher education ,  General/trade ,  Tertiary & Higher Education ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction. Single-Arm Phase II Trial Designs. Inference on the Binomial Probability in Single-Arm Multistage Clinical Trials. Single-Arm Phase II Clinical Trials with Time-to-Event Endpoints. Single-Arm Phase II Trials with Heterogeneous Patient Populations: Binary and Survival Outcomes. Randomized Phase II Trials for Selection: No Prospective Control Arms. Randomized Phase II Cancer Clinical Trials with a Prospective Control on Binary Endpoints (I): Two-Sample Binomial Test. Randomized Phase II Cancer Clinical Trials with a Prospective Control on Binary Endpoints (II): Fisher's Exact Test. Randomized Phase II Trials with Heterogeneous Patient Populations: Stratified Fisher's Exact Test. Randomized Phase II Clinical Trials Based on Survival Endpoints: Two-Sample Log-Rank Test. Some Flexible Phase II Clinical Trial Designs. Index.

Reviews

""Randomized Phase II Cancer Clinical Trials will be an invaluable source of information and reference for anyone interested in phase II cancer clinical trials, be it a graduate student, a biostatistics professor, or a cancer clinician in need of flexible designs and statistical analyses. … informative and interesting to read. The first of its kind, this book introduces the recent development of the promising randomized phase II trials. … This book has a very coherent structure and a legible style. … The author did an excellent job providing both contextual and technical details in a form that is both engaging and very readable. … a practical guidance book for cancer clinicians, as well as an excellent reference book for a more broad course, say, for example, clinical trials."" —Journal of the American Statistical Association, December 2014 ""… this book is very timely and it can help biostatisticians and oncologists design more elaborate cancer clinical trials. This book is well written and nicely organized to illustrate statistical concepts and methods in both single-arm and randomized phase II cancer clinical trials. … This book is certainly one of the best textbooks for a graduate-level clinical trial course in the biostatistics department. Also, oncologists with weak statistical background can easily understand the statistical concepts of the phase II cancer clinical trials since the author tries to explain the key concepts with many tables and figures instead of relying on equations."" —Biometrics, September 2014 ""… the book is unique in that it focuses solely on phase II cancer clinical trials with its emphasis on randomised trials. It goes far beyond what is covered on phase II clinical trials in cancer in books, for example, in Buyse et al. (1984) and more recently in Crowley & Hoering (2012) or Green et al. (2012). As such, it will definitely serve well as a reference for those involved in phase II cancer c


""Randomized Phase II Cancer Clinical Trials will be an invaluable source of information and reference for anyone interested in phase II cancer clinical trials, be it a graduate student, a biostatistics professor, or a cancer clinician in need of flexible designs and statistical analyses. … informative and interesting to read. The first of its kind, this book introduces the recent development of the promising randomized phase II trials. … This book has a very coherent structure and a legible style. … The author did an excellent job providing both contextual and technical details in a form that is both engaging and very readable. … a practical guidance book for cancer clinicians, as well as an excellent reference book for a more broad course, say, for example, clinical trials."" —Journal of the American Statistical Association, December 2014 ""… this book is very timely and it can help biostatisticians and oncologists design more elaborate cancer clinical trials. This book is well written and nicely organized to illustrate statistical concepts and methods in both single-arm and randomized phase II cancer clinical trials. … This book is certainly one of the best textbooks for a graduate-level clinical trial course in the biostatistics department. Also, oncologists with weak statistical background can easily understand the statistical concepts of the phase II cancer clinical trials since the author tries to explain the key concepts with many tables and figures instead of relying on equations."" —Biometrics, September 2014 ""… the book is unique in that it focuses solely on phase II cancer clinical trials with its emphasis on randomised trials. It goes far beyond what is covered on phase II clinical trials in cancer in books, for example, in Buyse et al. (1984) and more recently in Crowley & Hoering (2012) or Green et al. (2012). As such, it will definitely serve well as a reference for those involved in phase II cancer clinical trials, including clinical biostatisticians as well as clinical oncologists. … a useful reference in a graduate course in statistical methods for clinical trials."" —International Statistical Review (2014), 82 ""… an excellent book covering various practical phase II designs with their associated statistical methods for cancer clinical trials. It is an asset to statistical professionals who work at industry or academia and would like to learn more about or improve their understanding of phase II trial design and methods for cancer clinical trials. The book can also be used as a text book for graduate student with statistical major."" —Steven Sun, Janssen Research Development, New Jersey, USA ""Randomized Phase II Cancer Clinical Trials will be an invaluable source of information and reference for anyone interested in phase II cancer clinical trials, be it a graduate student, a biostatistics professor, or a cancer clinician in need of flexible designs and statistical analyses. … informative and interesting to read. The first of its kind, this book introduces the recent development of the promising randomized phase II trials. … This book has a very coherent structure and a legible style. … The author did an excellent job providing both contextual and technical details in a form that is both engaging and very readable. … a practical guidance book for cancer clinicians, as well as an excellent reference book for a more broad course, say, for example, clinical trials."" —Journal of the American Statistical Association, December 2014 ""… this book is very timely and it can help biostatisticians and oncologists design more elaborate cancer clinical trials. This book is well written and nicely organized to illustrate statistical concepts and methods in both single-arm and randomized phase II cancer clinical trials. … This book is certainly one of the best textbooks for a graduate-level clinical trial course in the biostatistics department. Also, oncologists with weak statistical background can easily understand the statistical concepts of the phase II cancer clinical trials since the author tries to explain the key concepts with many tables and figures instead of relying on equations."" —Biometrics, September 2014 ""… the book is unique in that it focuses solely on phase II cancer clinical trials with its emphasis on randomised trials. It goes far beyond what is covered on phase II clinical trials in cancer in books, for example, in Buyse et al. (1984) and more recently in Crowley & Hoering (2012) or Green et al. (2012). As such, it will definitely serve well as a reference for those involved in phase II cancer clinical trials, including clinical biostatisticians as well as clinical oncologists. … a useful reference in a graduate course in statistical methods for clinical trials."" —International Statistical Review (2014), 82 ""… an excellent book covering various practical phase II designs with their associated statistical methods for cancer clinical trials. It is an asset to statistical professionals who work at industry or academia and would like to learn more about or improve their understanding of phase II trial design and methods for cancer clinical trials. The book can also be used as a text book for graduate student with statistical major."" —Steven Sun, Janssen Research Development, New Jersey, USA


Randomized Phase II Cancer Clinical Trials will be an invaluable source of information and reference for anyone interested in phase II cancer clinical trials, be it a graduate student, a biostatistics professor, or a cancer clinician in need of flexible designs and statistical analyses. ... informative and interesting to read. The first of its kind, this book introduces the recent development of the promising randomized phase II trials. ... This book has a very coherent structure and a legible style. ... The author did an excellent job providing both contextual and technical details in a form that is both engaging and very readable. ... a practical guidance book for cancer clinicians, as well as an excellent reference book for a more broad course, say, for example, clinical trials. -Journal of the American Statistical Association, December 2014 ... this book is very timely and it can help biostatisticians and oncologists design more elaborate cancer clinical trials. This book is well written and nicely organized to illustrate statistical concepts and methods in both single-arm and randomized phase II cancer clinical trials. ... This book is certainly one of the best textbooks for a graduate-level clinical trial course in the biostatistics department. Also, oncologists with weak statistical background can easily understand the statistical concepts of the phase II cancer clinical trials since the author tries to explain the key concepts with many tables and figures instead of relying on equations. -Biometrics, September 2014 ... the book is unique in that it focuses solely on phase II cancer clinical trials with its emphasis on randomised trials. It goes far beyond what is covered on phase II clinical trials in cancer in books, for example, in Buyse et al. (1984) and more recently in Crowley & Hoering (2012) or Green et al. (2012). As such, it will definitely serve well as a reference for those involved in phase II cancer c


Author Information

Sin-Ho Jung is a professor of biostatistics and bioinformatics at Duke University School of Medicine. He earned a PhD from the University of Wisconsin-Madison. His research interests include clinical trial design, survival analysis, longitudinal data analysis, clustered data analysis, ROC curve analysis, and microarray studies.

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