Overview
Bradford Hill has defined a clinical trial as ""A carefully and ethically designed experiment with the aim of answering some precisely framed question"" [1]. This definition specifies a careful design and requires the provision of adequate controls. Random allocation of treatments to subjects is important to ensure is entitled that the treated and control groups are similar. Therefore this book Randomised Controlled Clinical Trials. We can define a randomised controlled trial by rewriting Bradford Hill's definition as follows, ""A carefully and ethi cally designed experiment which includes the provision of adequate and ap propriate controls by a process of randomisation, so that precisely framed questions can be answered. "" I am a firm advocate ofRandomised Controlled Clinical Trials but intend to give a balanced view of the advantages and disadvantages of these ethical experiments. This book is directed primarily at the medical research worker, although certain chapters may find a wider application. When discussing a randomised controlled trial, it is neither practicable nor desirable to divorce theory from practice, however the first ten chapters con centrate mainly on theory, and the remainder focus on practice. The segment on trial design is followed by sections on writing the protocol, designing the forms, conducting the trial, and analysing the results. This book is meant to serve both as a reference manual and a practical guide to the design and performance of a trial.
Full Product Details
Author: Christopher J. Bulpitt
Publisher: Springer-Verlag New York Inc.
Imprint: Springer-Verlag New York Inc.
Edition: Softcover reprint of the original 1st ed. 1983
Volume: 1
Dimensions:
Width: 15.50cm
, Height: 1.50cm
, Length: 23.50cm
Weight: 0.427kg
ISBN: 9781475763607
ISBN 10: 1475763603
Pages: 262
Publication Date: 08 March 2013
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
Reviews
`...a well-written basic introduction to the design and conduct of a clinical trial, referring to many cardiovascular examples along the way. It especially singles out topics of quality of life and failures of previous randomised trials. With that in mind, it is a useful contribution to a very important area in medical research.' Controlled Clinical Trials, 6 (1985)
`...a well-written basic introduction to the design and conduct of a clinical trial, referring to many cardiovascular examples along the way. It especially singles out topics of quality of life and failures of previous randomised trials. With that in mind, it is a useful contribution to a very important area in medical research.' Controlled Clinical Trials, 6 (1985)
'...a well-written basic introduction to the design and conduct of a clinical trial, referring to many cardiovascular examples along the way. It especially singles out topics of quality of life and failures of previous randomised trials. With that in mind, it is a useful contribution to a very important area in medical research.' Controlled Clinical Trials, 6 (1985)
