Overview
Protein oxidation by free radicals is thought to play a major role in many oxidative processes within cells, and is implicated in human disease, carcinogenesis, and ageing. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides, and proteins by free radicals and discusses the roles of such processes in biological systems. Topics include: the chemistry of amino acid and protein oxidation; the biochemical consequences of these reactions; the role of protein oxidation in normal physiology; the potential importance of protein oxidation in human health - including ageing, heart disease, cancer, inflammation and neurodegenerative diseases - and the possible prevention of such processes by antioxidants and other protective strategies.
Full Product Details
Author: Michael J. Davies (The Heart Research Institute, Sydney) ,
Roger T. Dean (The Heart Research Institute, Sydney)
Publisher: Oxford University Press
Imprint: Oxford University Press
Dimensions:
Width: 16.20cm
, Height: 2.70cm
, Length: 24.20cm
Weight: 0.804kg
ISBN: 9780198500971
ISBN 10: 0198500971
Pages: 456
Publication Date: 16 October 1997
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Out of Print
Availability: In Print
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.
Reviews
This is an excellent and long-overdue book...this excellent book should be widely read by everyone in the free radical field. I recommend it highly. * Halliwell, Free Rad.Res,Vol.29 * This comprehensive text includes a great deal of relevant information on this important topic and discusses protein oxidation in many biological systems. * Aslib Book Guide, vol.63, no.2, Feb.98 *
True to its title, this book provides an excellent and broad overview of recent advances in radical-dependent oxidation of proteins . . . Its breadth of coverage and extensive (bordering on comprehensive) citation of the literature . . . makes this a definitive source for experts in the field. The lucid presentation will be similarly attractive to students and professionals with little knowledge of this topic. Valuable tables containing information such as radical mechanisms and products, reaction rate constants, and oxidized amino acids in human tissue have been created to integrate and summarize the salient features of numerous investigations. Most importantly, the authors do not merely compile the results and conclusions of others; instead they provide extensive commentary and critical evaluation of their subjects. This unusually well-written monograph should now be considered the primer for studies on protein oxidation. --The Quarterly Review of Biology<br>
Author Information
Professor Roger T. Dean, Director, The Heart Research Institute Ltd, 145-147 Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia. Tel: 0061 2 550 3560. Fax: 0061 2 550 3302. Email: r.dean@hri.edu.au Dr Michael Davies at the same address
