Pyrazolo Pyrimides-Based Drug Discovery
Author:   Rajshekhar Karpoormath (Research Group, University of KwaZulu-Natal, South Africa)
Publisher:   Elsevier Science Publishing Co Inc
ISBN:  

9780128238875


Pages:   370
Publication Date:   01 April 2023
Format:   Paperback
Availability:   In Print   Availability explained
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Pyrazolo Pyrimides-Based Drug Discovery


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Author:   Rajshekhar Karpoormath (Research Group, University of KwaZulu-Natal, South Africa)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Elsevier Science Publishing Co Inc
ISBN:  

9780128238875


ISBN 10:   0128238879
Pages:   370
Publication Date:   01 April 2023
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

1. Title 2. Introduction 3. Marketed drugs containing pyrazolo pyrimidine scaffold 4. Pharmacological activities along with SAR 5. Importance of functionalization 6. Conclusion 7. Future Scope 8. References

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Rajshekhar Karpoormath's research group at University of KwaZulu-Natal, South Africa specialises on the synthesis of aza-heterocycles and their pharmacological applications. One such versatile scaffold of our research interest is pyrazolopyrimidines and their broad range of medicinal applications. We have published several review articles on aza-heterocycles and recently published two full review articles in European Journal of Medicinal Chemistry (2017) 126, 298-352 and Bioorganic & Medicinal Chemistry (2018), 26(2), 309-339 on pyrazolo[1,5-a]pyrimidine and pyrazolo[4,3-d]pyrimidine scaffolds respectively. Our exercise of writing the two reviews on pyrazolopyrimidine analogues has given us good understanding and knowledge on this scaffold. In addition we have studied and collected extensive literature on this topic, thus having required credentials and knowledge in writing an extensive book on pyrazolopyrimidine with special emphasis on their medicinal applications and Structure Activity Relationship (SAR) Studies.

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