Overview

This study investigates how psychotropic drugs influence anterior pituitary hormone (APH) secretion in healthy subjects and depressed patients. The study was designed to find out if psychotropic drugs with differing pharmacological actions also influence APH secretion differently. The examinations are presented in detail and enable the reader to follow the strategy, check the data, and interpret the results. The authors ask whether it is possible to draw from the data conclusions about the effects of drugs such as antidepressants, neuroleptics, and benzodiazepine-type tranquilizers on certain neurons in the human body. The comparisons between healthy individuals and neurotic or endogenous depressed patients provide interesting results, some of which hint at a disturbed metabolism in the patients suffering from depression.

Full Product Details

Author:   Gregor Laakmann
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Dimensions:   Width: 15.50cm , Height: 1.20cm , Length: 23.50cm
Weight:   0.359kg
ISBN:  

9783540520757

ISBN 10:   3540520759
Pages:   219
Publication Date:   05 October 1990
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

1 Introduction.- 1.1 Outline of the Study.- 1.2 Effect of Psychotropic Drugs on Central Nervous Aminergic Stimuli Transmission.- 1.3 Influence of Aminergic Neuronal Systems on Anterior Pituitary Hormone Secretion.- 1.4 Aminergic Neurons, APH Secretion and Depression Research.- 2 Influence of Psychotropic Drugs on Anterior Pituitary Hormone Secretion in Healthy Subjects.- 2.1 Healthy Subjects and Methods.- 2.2 Influence of Psychotropic Drugs on GH Secretion.- 2.3 Influence of Psychotropic Drugs on Prolactin Secretion.- 2.4 Influence of Psychotropic Drugs on Cortisol/ACTH Secretion.- 2.5 Discussion.- 3 Influence of Receptor Blockers and Receptor Agonists on Antidepressant-Induced Anterior Pituitary Hormone Secretion in Healthy Subjects.- 3.1 Healthy Subjects and Methods.- 3.2 Influence of Receptor Blockers and Receptor Agonists on DMI-Induced GH Stimulation.- 3.3 Influence of Receptor Blockers and Receptor Agonists on DMI-Induced PRL Stimulation.- 3.4 Influence of Receptor Blockers and Receptor Agonists on DMI-Induced Cortisol/ACTH Stimulation.- 3.5 Discussion.- 4 Desipramine-Induced Growth Hormone Stimulation in Depressive Patients and Healthy Subjects.- 4.1 GH Secretion after Desipramine in Depressive Patients and Healthy Subjects.- 4.2 Healthy Subjects, Patients, and Methods.- 4.3 Results.- 4.4 Summary and Discussion.- 5 Summary.- 6 Reference.

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