Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development

Author:   H. John Smith ,  Claire Simons
Publisher:   Taylor & Francis Ltd
ISBN:  

9780415273497


Pages:   436
Publication Date:   28 March 2002
Format:   Hardback
Availability:   In Print   Availability explained
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Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development


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Overview

Cellular proteinases and their physiological role in normal and disease states have been the subject of great interest over recent decades. At present, specific protease inhibitors are exploited both as tools in unraveling the role of individual proteinases in particular cellular processes and for the development of chemotherapeutic agents for the treatment of various disorders. Proteinase and Peptidase Inhibition presents updated progress reports on the characterization of a wide range of cellular proteinases whose inhibitors may hold the key to the development of new drugs. Introductory chapters deal with the broad enzyme classes, inhibitor types and regulatory mechanisms governing proteinase activity. The target enzymes themselves, together with all aspects of their inhibition and inhibitor design, are comprehensively described. The classification of target enzymes by structural similarity, rather than by pharmacological effects, provides a new and coherent platform for understanding how inhibition of different targets can lead to the same therapeutic outcomes. This is a valuable reference book that will appeal to both academic and industrial researchers in the fields of medicinal chemistry, drug design and development, pharmacology, biochemistry, and molecular and cell biology.

Full Product Details

Author:   H. John Smith ,  Claire Simons
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Dimensions:   Width: 17.80cm , Height: 2.50cm , Length: 25.40cm
Weight:   1.006kg
ISBN:  

9780415273497


ISBN 10:   0415273498
Pages:   436
Publication Date:   28 March 2002
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Smith, H. John; Simons, Claire

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