Overview

This book will consider principles of the organization of protein molecules, the relationships between primary, secondary, and tertiary structure, the determinants of protein conformation, and the applications of structure determination and structure modeling in biomedical research.

Full Product Details

Author:   Natalya Kurochkina
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2019
Weight:   0.704kg
ISBN:  

9789811366000

ISBN 10:   9811366004
Pages:   276
Publication Date:   18 June 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

CHAPTER 1 - Protein Structure 1.1 Polypeptide chain 1.2 Ligand binding 1.3 Active site 1.3 Structure-function CHAPTER 2 - Conformational transitions 2.1 Types of transitions in molecular systems 2.2 Conformational states 2.3 Quantum motions 2.4 Myoglobin and hemoglobin 2.5 Cytochromes 2.6 Tobacco mosaic virus coat protein 2.7 Fibrin-fibrinogen 2.8 Conformational changes of side chains in protein interior as a basis of the conformational states of the molecule CHAPTER 3 - Allosteric regulation 3.1 Proteins 3.2 Nucleic acids 3.3 Small ligands CHAPTER 4 - Protein channels 4.1 Structure-function 4.2 Signaling CHAPTER 5 - Helical assemblies 5.1 Determinants of specific helix recognition 5.2 Types of assemblies CHAPTER 6 - multiprotein complexes 6.1 Postsynaptic density 6.2 Viruses 6.3 Implications in signaling CHAPTER 7 - Methods of structure determination 7.1 X-Ray crystallography, NMR and Electron Microscopy 7.2 NMR 7.3 Electron Microscopy CHAPTER 8 - Protein modeling 8.1 Helix and its interactions 8.2 Ligands 8.3 Dynamics References Dictionary

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