Protein Structural Biology in Biomedical Research, Part A
Author:   C. Woodward (Department of Biochemistry, University of Minnesota, St. Paul, MN, USA) ,  N.M. Allewell (Department of Biochemistry, University of Minnesota, St. Paul, MN, USA) ,  E. Edward Bittar
Publisher:   Elsevier Science & Technology
Volume:   22
ISBN:  

9780762302833


Pages:   626
Publication Date:   16 January 1998
Format:   Hardback
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

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Protein Structural Biology in Biomedical Research, Part A


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Overview

This text covers aspects of protein structural biology which have led to recognition of fundamental relationships between protein structure and function. The first two chapters, for example, are concerned with identification and design of specific ligand binding site. Chapter 1, ""Protein Crystallography in Medicine"" describes medically-relevant proteins for which crystal structures have provided targets for drug design. Chapter 2 introduces strategies used in design of proteins with specified binding capabilities, and chapter 3 explores the most useful depictions of protein structure. Other topics covered in the rest of the book include ""threading""; the mathematical basis for probabilistic methods and the application of molecular dynamics simulations to problems of molecular recognition.

Full Product Details

Author:   C. Woodward (Department of Biochemistry, University of Minnesota, St. Paul, MN, USA) ,  N.M. Allewell (Department of Biochemistry, University of Minnesota, St. Paul, MN, USA) ,  E. Edward Bittar
Publisher:   Elsevier Science & Technology
Imprint:   JAI Press Inc.
Volume:   22
Dimensions:   Width: 15.60cm , Height: 2.00cm , Length: 23.40cm
Weight:   0.660kg
ISBN:  

9780762302833


ISBN 10:   0762302836
Pages:   626
Publication Date:   16 January 1998
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Protein Crystallography in Medicine (M.J. Rynkiewicz and B.A. Seaton). Engineering Metal Binding Sites in Proteins (L. Regan). Using Molecular Graphics to Analyze Protein Structures (H. Oberoi and N.M. Allewell). Electrostatics and Hydrogen Bonding (B. Garcia-Moreno E.). Protein Structure Determination by Nuclear Magnetic Resonance Spectroscopy (I.M. Russu). Membrane Protein Structure (M.P. McCarthy). Structural Features of Membrane Proteins (T. Haltia). Experimental Dissection of Protein-Protein Interactions in Solution (M.L. Doyle and P. Hensley).

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