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Author:   Martin Zacharias (Technische Univ Munchen, Germany)
Publisher:   Imperial College Press
Imprint:   Imperial College Press
Dimensions:   Width: 15.20cm , Height: 1.80cm , Length: 22.60cm
Weight:   0.612kg
ISBN:  

9781848163393

ISBN 10:   1848163398
Pages:   400
Publication Date:   10 May 2010
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Introduction to Protein-Protein Interactions: Protein-Protein Complex Determination by X-ray Crystallography and Interface Analysis of Known Structures (J Janin); Protein-Protein Complex Determination and Analysis of Interactions Using NMR Spectroscopy (J Werner); Perspective on Protein-Protein Interactions in Macromolecular Assemblies (R Bahadur); Energetics of Protein-Protein Interactions (I Jelezarov); Kinetics of Complex Formation: Theory and Experiment (R Wade); Prediction of Putative Protein Interaction Regions and Interaction Geometries: Prediction of Protein Interaction Regions Based on Evolutionary Information (O Lichtarge); Prediction of Interaction Regions and Scoring Optimization (M Zacharias); Protein-Protein Docking Methods: A General Overview (C Prevost); Refinement of Docking Solutions (C Camacho); High-Resolution Docking Including Conformational Flexibility (O Furman); Experimental Constraint-Driven Docking (A Bonvin); Design and Targeting of Protein-Protein Interactions by Drugs and Protein Mimetics: Protein-Protein Interaction Modules of Medical Importance (H Sticht); Prediction/Calculation of Protein-Protein Binding Affinities and Mutation Effects (Fiorucci et al.); Design of Protein Mimetics That Interfere with Protein-Protein Interactions (K Mayo); Identifying Molecules to Inhibit Protein-Protein Interactions (T Berg); Combining Bioinformatics and Experiment to Design Inhibitors of Protein-Protein Interactions (G Colombo).

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