Protein Degradation in Health and Disease
Author:   Michele Reboud-Ravaux
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Volume:   v. 29
ISBN:  

9783540425946


Pages:   140
Publication Date:   January 2002
Format:   Hardback
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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Protein Degradation in Health and Disease


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Overview

Protein degradation has been identified as a major mechanism for the regulation of cellular functions. Not surprisingly, its deregulation is implied in almost any pathological condition. This book describes how aged proteins are eliminated during cell metabolism, how cell proliferation is regulated by protein degradation and how its deregulation can contribute to the development of cancer, how protein degradation is modified during normal and abnormal aging, in particular with regard to Alzheimer's disease and other degenerative diseases of the brain and central nervous system. Attempts aiming at correcting these pathologies by interfering with deviations of the normal pathway of protein degradation are also treated.

Full Product Details

Author:   Michele Reboud-Ravaux
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Volume:   v. 29
Dimensions:   Width: 15.70cm , Height: 1.30cm , Length: 23.00cm
Weight:   0.331kg
ISBN:  

9783540425946


ISBN 10:   3540425942
Pages:   140
Publication Date:   January 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Roles of SCF and VHL Ubiquitin Ligases in Regulation of Cell Growth * Aging of Proteins and the Proteasome * Pathways of Protein Degradation and How They Are Affected by Age * Protein Degradation in Alzheimer's Disease and Aging of the Brain * Protein Degradation in Human Disease * The 26S Proteasome * Proteasome Inhibitors.

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