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Author:   Eaton E. Lattman (Hauptman-Woodward Institute) ,  Patrick J. Loll (Director, Biochemistry Graduate Program, Drexel University College of Medicine)
Publisher:   Johns Hopkins University Press
Imprint:   Johns Hopkins University Press
Dimensions:   Width: 15.20cm , Height: 1.00cm , Length: 22.90cm
Weight:   0.227kg
ISBN:  

9780801888083

ISBN 10:   0801888085
Pages:   152
Publication Date:   23 June 2008
Recommended Age:   From 13
Audience:   College/higher education ,  Tertiary & Higher Education ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   To order  
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Table of Contents

Preface 1. Introduction 1.1. What Is X-ray Crystallography? 1.2. A Quick Look at Protein Crystals 1.3. Noncrystalline Specimens 1.4. Summary Further Reading 2. A Physical Understanding of Diffraction 2.1. What Is Diffraction? 2.2. Diffraction from One-Dimensional Crystals 2.3. Reconstructing Images from Diffraction Patterns 2.4. Summary Further Reading 3. Diffraction from Three-Dimensional Crystals 3.1. The Electron Density Function in Three Dimensions 3.2. Calculating the Diffraction Pattern from a Known Structure 3.3. Summary Further Reading 4. Phase Determination by Isomorphous Replacement 4.1. Measuring the Phases 4.2. MAD Phasing 4.3. Fitting Models to Experimental Electron Density Maps 4.4. Summary Further Reading 5. The Patterson Function 5.1. Definition of the Patterson Function 5.2. Using the Patterson Function to Locate Atoms 5.3. Summary Further Reading 6. Phasing with Partially Known Structures 6.1. Difference Fourier Maps 6.2. Molecular Replacement 6.3. Summary Further Reading 7. Crystallographic Refinement 7.1. Refinement Improves the Model 7.2. Least-Squares Refinement 7.3. Summary Further Reading Glossary Index

Reviews

A useful source. Choice It is gratifying to see such a nice piece of work and the book is highly recommended. -- Eddie Snell Reflexions: Newsletter of the American Crystallographic Association One of the main assets of the book is its many illustrations. Without exception the figures are straightforward to interpret, and the visual support enables the newcomers to the field to follow the presented material easily. -- Linda Schuldt and Manfred S. Weiss Crystallography Reviews

It is gratifying to see such a nice piece of work and the book is highly recommended. -- Eddie Snell, Reflexions: Newsletter of the American Crystallographic Association

Author Information

Eaton E. Lattman is chair of the Department of Biophysics at the Johns Hopkins University and editor-in-chief of the journal Proteins: Structure, Function, and Genetics. Patrick J. Loll is the director of the Biochemistry Graduate Program at Drexel University College of Medicine.

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