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Full Product Details

Author:   John C. Cheronis ,  John E. Repine
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Volume:   42
Weight:   0.645kg
ISBN:  

9783764328689

ISBN 10:   3764328681
Pages:   248
Publication Date:   May 1993
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Overview.- Proteases - Structures, Mechanisms and Inhibitors.- Biochemical Mechanisms for Disrupting the Proteinase-Proteinase Inhibitor Balance in Tissues.- Oxidants, Metalloproteases and Serine Proteases in Inflammation.- Elastase and Oxygen Radicals: Synergistic Interactions.- Neutrophil Elastase Inhibitors: Clinical Potential.- Proteolysis-Induced Pathomechanisms in Acute Inflammation and Related Therapeutic Approaches.- Synthesis and Characterization of Human Neutrophil Elastase Inhibitors Derived from Aromatic Esters of Phenylalkanoic Acids.- In Vivo Evaluation of MDL 201,404YA, A Novel Inhibitor of Human Neutrophil Elastase.- Alpha1-Antitrypsin Augmentation Therapy.- Secretory Leukocyte Protease Inhibitor in Cystic Fibrosis.- Oxidation Resistant Muteins of Antileukoproteinase as Potential Therapeutic Agents.- Proteases and Protease-Derived Peptides in Inflammation.- Factor XII Activation and Inhibition in Inflammation.- The Kinin System in Inflammation.- Role of Bradykinin in Microbial Infection: Enhancement of Septicemia by Microbial Proteases and Kinin.- Kinin Antagonists as Human Therapeutics.- Proteases in Immunoregulation and Cellular Differentiation.- Cytokine Regulation of Endothelial Cell Extracellular Proteolysis.- Different Functional Share of Individual Lysosomal Cathepsins in Normal and Pathological Conditions.- Neuropeptide Processing in Pathophysiology.- Resolution of limp-Free and Timp-Complexed 70kDa Progelatinase from Culture Medium of Rous Sarcoma Virus-Transformed Chicken.- Endotoxin and Eicosanoids.

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