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OverviewProstate Cancer provides an up-to-date review of the biochemistry, molecular biology, and genetic changes in prostate cells that are the driving forces in the initiation and progression of cancer. It includes an overview by experts in the field of cell-cell interactions, including stem cells, reactive Stromal cells and membrane lipid rafts that are instrumental in the initiation and progression of prostate cancer. Full Product DetailsAuthor: Donald J. TindallPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2013 ed. Volume: 16 Dimensions: Width: 15.50cm , Height: 2.70cm , Length: 23.50cm Weight: 8.015kg ISBN: 9781489986627ISBN 10: 1489986626 Pages: 522 Publication Date: 23 June 2015 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsPreface.- Section 1: Cell Biology.- Stem Cells in the Normal and Malignant Prostate.- Role of Reactive Stroma in Prostate Cancer.- The Role of Cholesterol in Prostate Cancer.- Section 2: Genetics: PTEN in Prostate Cancer.- ETS fusion genes in prostate cancer.- Section 3: Cell Signaling.- Signaling Mechanisms of Vav3, a Guanine Nucleotide Exchange Factor and Androgen Receptor Coactivator, in Physiology and Prostate Cancer Progression.- Transforming Growth Factor-beta (TGF-b) in Prostate Cancer.- The p38 MAPK Pathway in Prostate Cancer.- NF-kappaB2/p52 in Prostate Cancer.- The functional role of DAB2IP, a homeostatic factor, in prostate cancer.- Tyrosine Kinases in Prostate Cancer.- Human prostatic acid phosphatase in prostate carcinogenesis.- Section 4: Hormonal.- Truncated Androgen Receptor Splice Variants in Prostate Cancer.- Biology and Clinical Relevance of Estrogen Receptors in Prostate Cancer.- Vitamin D and Prostate Cancer.- HDAC6 regulation of androgen signaling in prostate cancer.- Beyond the cell cycle: Implications of D-type cyclin deregulation in Pca.- Section 5: Cell Death.- Role of Par- in Prostate Cancer.- Autophagy and Prostate Cancer Therapeutics.- Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |