Overview

This text covers the complex structure of cells and how they signal to each other when the body is infected with cancer. Head and neck cancer is covered in detail to illustrate a cancer in humans where these considerations are particularly relevant. This volume demonstrates that the principal factor in cancer patient immunologic defiency is related to excess secretion of monocytes of prostaglandins. The text explains how a cancer patient's immunologic defiency may be largely related to abnormalities of monocyte eicosanoid metabolism, and provides successful methods and approaches to augment anti-tumour immunity in cancer patients by inhibiting various pathways in eicosanoid metabolism.

Full Product Details

Author:   Jules E. Harris ,  Donald P. Braun ,  Kenning M. Anderson ,  William L. Smith
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Weight:   0.560kg
ISBN:  

9780849369032

ISBN 10:   0849369037
Pages:   256
Publication Date:   28 March 1994
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Cyclooxygenase and Lipoxygenase Pathways of Arachidonic Acid Metabolism (W.L. Smith and O. Laneuville). Participation of Lipoxygenase Products in Lymphohematopoietic and Other Cell Proliferation and Differentiation (K.M. Anderson, M. Wiederhold, and F. Ondrey). Eicosanoids and Tumor Cell Metastasis (D.G. Tang and K.V. Honn). The Impact of Prostaglandins on Cancer Patient Immunity (D.P. Braun and J.E. Harris). Prostaglandins and Host Immune Response in Squamous Cell Carcinoma of the Head and Neck (D.S. Cross, F. Ondrey, S.K. Juhn, and G.L. Adams). Eicosanoid-Induced Radioprotection and Chemoprevention of Normal Tissue During Cancer Treatment (W.R. Hanson). Prostaglandins and the Host Immune System: Application of Prostaglandin Inhibitors for Cancer Immunotherapy (P.K. Lala and M.-N. Saarloos).

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Jules E. Harris, Donald P. Braun, Kenning M. Anderson

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