Progress in Total Synthesis: Volume 1

Author:   Sarah Danishefsky
Publisher:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1971
ISBN:  

9781468481860


Pages:   266
Publication Date:   12 June 2012
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Progress in Total Synthesis: Volume 1


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Overview

This series stemmed from a group of weekly seminars in our research group aimed at keeping its members abreast of recent developments in organic synthesis. The seminars tended to consist of several syntheses of natural products or related systems with particular emphasis on the general strategy inherent in the effort, new and interesting reactions which were utilized in the work, and specificity (or the lack of it) in arranging the relative stereochemistry of asymmetric centers and the geometry of double bonds. We found that natural products offered an attractive setting in which the larger science of organic chemistry could be put to crucial tests. A truly elegant synthesis is a major advance in that it epitomizes how an imaginative mastery of the course of organic reactions can achieve a sophisticated objective by an economy of operations. Indeed any successful synthesis of a reasonably complex product, however cumbersome and graceless, is an important event for those who delight in the problem-solving dimension of science.

Full Product Details

Author:   Sarah Danishefsky
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1971
Dimensions:   Width: 17.80cm , Height: 1.50cm , Length: 25.40cm
Weight:   0.537kg
ISBN:  

9781468481860


ISBN 10:   146848186
Pages:   266
Publication Date:   12 June 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

I. Alkaloids and Intermediates in the Synthesis of Alkaloids.- 1. Acronycine.- 2. Ajaconine and Atidine Intermediates.- 3. Androcymbine-Type Compounds.- 4. Apoferrorosamine and Myosmine.- 5. 6,7-Benzomorphan.- 6. Condyfoline, Tubifoline, and Tubifolidine.- 7. Coreximine.- 8. (-)-Corynantheidine.- 9. (3S, 15S, 20R)-Corynantheine.- 10. Dasycarpidone and Epidasycarpidone.- 11. Dasycarpidone and Epidasycarpidone.- 12. Dihydrocrinine and Dihydrovittatine.- 13. Dihydrogambirtannine and Aspidosperma-Strychnos Alkaloid Models.- 14. 15,16-Dimethoxyerythrinan-3-One.- 15. Synthetic Approaches to Diterpene Alkaloids.- 16. Diterpene Alkaloid Intermediates.- 17. Diterpene Alkaloids.- 18. Epiibogamine and Ibogamine.- 19. Epiibogamine.- 20. Synthesis of Ring Systems Related to Hasubanan Alkaloids.- 21. Hernadine.- 22. Homoerythrinadienone.- 23. Homoproaporphine-Type Compounds.- 24. ?,?-Disubstituted Indoline Derivatives.- 25. 17-Acetyl-5?-Etiojerva-12,14,16-Trien-3?-OL.- 26. Lupinine and Epilupinine and the Hydrolulolidine and Hydrojulolidine Ring Systems.- 27. 12-Epilycopodine.- 28. Lycopodine.- 29. Lycopodine.- 30. Mesembrine.- 31. Mesembrine.- 32. Mesembrine.- 33. Mesembrine.- 34. Mesembrine.- 35. Ochotensine and Ochotensimine.- 36. Ochotensimine.- 37. Perlolidine.- 38. Petaline.- 39. Quebrachamine Skeleton.- 40. Sanguinarie.- 41. Sempervirine Hydrobromide.- 42. Solanidine.- 43. Stebisimine.- 44. Veatchine.- 45. Velbanamine.- 46. Verarine.- 47. Monomeric Vinca Alkaloids-Vincadine, Vincaminoreine, Vincaminorine, Vincadifformine, and Minovine.- 48. Dimeric Vinca Alkaloids.- 49. Vincaminol.- 50. 1-Methyl-16-Demethoxycarbonyl-20-Desethylidene-Vobasine.- 51. Withasomnine.- 52. Withasomnine.- II. Terpenes and Related Structures.- A. Monoterpenes.- B. Sesquiterpenes.- C. Diterpenes.-D. Triterpenes.- III. Other Natural Products.- A. Antibiotics and Metabolites.- B. Cannabinols.- C. Juvenile Hormones and Propylure.- D. Porphyrins.- E. Prostaglandins.- F. Steroids and Related Systems.- G. Zearalenones.

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