Progress in Heterocyclic Chemistry (PHC)

Author:   R Alan Aitken (Professor of Organic Chemistry, School of Chemistry, University of St Andrews, UK) ,  Justin M. Lopchuk (Associate Member & Professor, Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, USA)
Publisher:   Elsevier - Health Sciences Division
Volume:   36
ISBN:  

9780443334948


Pages:   700
Publication Date:   01 November 2024
Format:   Paperback
Availability:   Not yet available   Availability explained
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Progress in Heterocyclic Chemistry (PHC)


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Overview

Progress in Heterocyclic Chemistry (PHC), Volume 36 is the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new and developing topics of particular interest to heterocyclic chemists. The highlight chapters in this volume are all written by leading researchers in their fields, and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2023. As with previous volumes in the series, this update will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way.

Full Product Details

Author:   R Alan Aitken (Professor of Organic Chemistry, School of Chemistry, University of St Andrews, UK) ,  Justin M. Lopchuk (Associate Member & Professor, Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, USA)
Publisher:   Elsevier - Health Sciences Division
Imprint:   Elsevier - Health Sciences Division
Volume:   36
ISBN:  

9780443334948


ISBN 10:   0443334943
Pages:   700
Publication Date:   01 November 2024
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Forthcoming
Availability:   Not yet available   Availability explained
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.

Table of Contents

1. Synthesis and Therapeutic Potential of C-2 Substituted 3,4-Dhydropyrimidines with Anticancer and Antioxidant Potential 2. Recent Advances in Energetic Heterocyclic Compounds 3. Three-Membered Ring Systems 4. Four-Membered Ring Systems 5.1 Five-Membered Ring Systems: Thiophenes and Selenium/Tellurium Analogs and Benzo Analogs 5.2 Five-Membered Ring Systems: Pyrroles and Benzo Analogs 5.3 Five-Membered Ring Systems: Furans and Benzofurans 5.4 Five Membered Ring Systems: With More than One N Atom 5.5 Five Membered Ring Systems: With N and S Atoms 5.6 Five-Membered Ring Systems: With O & S (Se, Te) Atoms 5.7 Five-Membered Ring Systems: With O & N Atoms 6.1 Six-membered ring systems: Pyridines and Benzo Derivatives 6.2 Six-Membered Ring Systems: Diazines and Benzo Derivatives 6.3 Triazines, Tetrazines and Fused Ring Polyaza Systems 6.4 Six-Membered Ring Systems: With O and/or S Atoms 7. Seven-Membered Rings 8. Eight-Membered and Larger Rings

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Author Information

Alan Aitken is a Professor of Organic Chemistry at the University of St Andrews, UK. Much of his research activity has been in the area of heterocyclic chemistry and he has been active in the International Society of Heterocyclic Chemistry, attending all but two of their biennial congresses since 1985, contributing an annual review chapter to Progress in Heterocyclic Chemistry since 1990 and being an elected member of their International Advisory Committee 1997–99 and 2011–17. Since 2018, he has been a member of the Executive Committee and Publicity Chair for ISHC. Justin grew up in Clifton, New Jersey and obtained a dual B. S. in Chemistry and Biology from Muhlenberg College in Allentown Pennsylvania. His Ph.D. studies were conducted at Dartmouth College in the laboratory of Prof. Gordon Gribble with a focus on heterocyclic chemistry and the synthesis of indole-containing natural products. He completed postdoctoral work on the synthesis of diterpenoid natural products and strain-release functionalization at The Scripps Research Institute under the guidance of Prof. Phil Baran. Justin began his independent career at Moffitt Cancer Center where his group focuses on the development of new methods for C–C, C–N, and C–S bond formation, the design of new covalent reactive groups, the total synthesis of bioactive natural products, and the structure-based drug design of small molecule inhibitors and PROTACS.

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