Overview
This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for clinicians seeing patients. It is also a stepping stone for new investigations and studies that goes beyond the facts about the composition and biochemistry of the connective tissue and extracellular matrix, as the authors connect individual components to specific aspects of various soft tissue disorders and to the actual or potential treatment of them. Progress in Heritable Soft Connective Tissue Diseases features very prominent physicians and scientists as contributors who bring their most recent discoveries to the benefit of readers. Their expertise will help clinicians with proper diagnosis of sometimes elusive and uncommon heritable diseases of soft connective tissues. This book also offers an update on the pathophysiology of these diseases, including an emphasis on unifying aspects such as connections between embryonic development of the different types of connective tissues and systems, and the role of TGF-beta in development and physiology of soft tissues. This new set of data explains, at least in part, why many of these disorders are interconnected, though the primary pathophysiological events, such as gene mutations, may be different for each disorder.
Full Product Details
Author: Jaroslava Halper
Publisher: Springer
Imprint: Springer
Edition: Softcover reprint of the original 1st ed. 2014
Volume: 802
Weight: 4.873kg
ISBN: 9789402407747
ISBN 10: 940240774
Pages: 245
Publication Date: 18 September 2016
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: In Print
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Reviews
From the reviews: This is a compilation of recent information on the area of connective tissue disorders and the human pathology involved. ... The audience is vast, from clinicians involved in the diagnosis and treatment of patients with connective tissue anomalies to primary care physicians in search to update their knowledge ... . This is an outstanding resource for trainees in medical genetics at all levels, as well as for experienced medical geneticists. (Luis F. Escobar, Doody's Book Reviews, May, 2014)
From the reviews: This is a compilation of recent information on the area of connective tissue disorders and the human pathology involved. ... The audience is vast, from clinicians involved in the diagnosis and treatment of patients with connective tissue anomalies to primary care physicians in search to update their knowledge ... . This is an outstanding resource for trainees in medical genetics at all levels, as well as for experienced medical geneticists. (Luis F. Escobar, Doody's Book Reviews, May, 2014)
From the reviews: This is a compilation of recent information on the area of connective tissue disorders and the human pathology involved. ... The audience is vast, from clinicians involved in the diagnosis and treatment of patients with connective tissue anomalies to primary care physicians in search to update their knowledge ... . This is an outstanding resource for trainees in medical genetics at all levels, as well as for experienced medical geneticists. (Luis F. Escobar, Doody's Book Reviews, May, 2014)
