Profiles of Drug Substances, Excipients and Related Methodology

Author:   Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA) ,  Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA) ,  Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA) ,  Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA)
Publisher:   Elsevier Science Publishing Co Inc
Edition:   35th edition
Volume:   v. 32
ISBN:  

9780122608322


Pages:   302
Publication Date:   20 December 2005
Format:   Hardback
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

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Profiles of Drug Substances, Excipients and Related Methodology


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Overview

Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism.

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Author:   Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA) ,  Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA) ,  Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA) ,  Harry G. Brittain (Center for Pharmaceutical Physics, Milford, NJ, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   35th edition
Volume:   v. 32
Dimensions:   Width: 16.50cm , Height: 1.90cm , Length: 24.00cm
Weight:   0.680kg
ISBN:  

9780122608322


ISBN 10:   0122608321
Pages:   302
Publication Date:   20 December 2005
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Profiles of Drug Substances 1. Miconazole Nitrate Comprehensive Profile. 2. Niclosamide Comprehensive Profile. 3. Oxytetracycline Analytical Profile 4. Penicillamine 4A. Physical Profile 4B. Analytical Profile 4C. ADME Profile 5. Primaquine Diphosphate Comprehensive Profile 6. Valproic Acid and Sodium Valproate Comprehensive Profile Related Methodology Review Article 7. Validation of Chromatographic Methods of Analysis Annual Review 8. Polymorphism and Solvatomorphism 2004

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Author Information

Dr. Brittain is presently the Institute Director of the Center for Pharmaceutical Physics, a research and consulting institute he established in 1999 for the study of substances having pharmaceutical interest. His research interest include all areas of pharmaceutical physics and physical pharmacy, including preformulation, formulation design, product characterization, polymorphism, solvatomorphism, and cocrystals of drug substances. Formerly, Dr. Brittain was Vice President for Pharmaceutical Development of Discovery Laboratories, Inc., he served as Director of Pharmaceutical Development at Ohmeda, Inc., and also led a variety of groups within the Analytical R&D department at Bristol-Myers Squibb. Dr. Brittain is a graduate of Queens College (B.A. in chemistry, 1970; M.A. in physical chemistry 1972), and of the City University of New York (Ph.D. in physical chemistry, 1975). He was a postdoctoral fellow at the University of Virginia, and has held full-time faculty positions at Ferrum College (Assistant Professor of Chemistry) and Seton Hall University (Associate Professor of Physical and Inorganic Chemistry). He has been Adjunct Professor of Pharmaceutics at Rutgers University, and both Adjunct Professor of Chemistry and Visiting Research Scientist at Lehigh University. Dr. Brittain has authored over 340 research publications and book chapters, and has presented over 175 invited lectures and short courses in the pharmaceutical field. He has edited the monographs Analytical Applications of Circular Dichroism, Physical Characterization of Pharmaceutical Solids, Polymorphism in Pharmaceutical Solids (first and second editions), Spectroscopy of Pharmaceutical Solids, and Preformulation in Solid Dosage Form Development. He is also the Editor-In-Chief of the book series Profiles of Drug Substances, Excipients, and Related Methodology, having edited 23 published volumes in the series that is now published annually by Elsevier. Dr. Brittain is also an Editor of Physical Pharmacy for the Journal of Pharmaceutical Sciences, and is a co-author of 22 issued United States patents. During his academic tenure at Seton Hall University, in 1980 Dr. Brittain was named as one of the Teacher-Scholars of the Camille and Henry Dreyfus Foundation. Dr. Brittain was elected as a Fellow of the American Association of Pharmaceutical Sciences (AAPS) in 1991, and received the AAPS Research Achievement Award in Analysis and Pharmaceutical Quality in 1998. He is also a Fellow of the Royal Society of Chemistry.

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