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Overview"Prions, probably the most fascinating proteins ever studied, have been in the spotlight for the last 30 years. However, their history is much older. Indeed, the symptoms of what are now known as prion diseases were first described in Europe in sheep in 1730 and called ""scrapie"" in England, ""vertige"" in France and ""Traberkrankheit"" in Germany. This book discusses the development of prions and their various diseases." Full Product DetailsAuthor: Jean-Michel VerdierPublisher: Nova Science Publishers Inc Imprint: Nova Science Publishers Inc Weight: 0.602kg ISBN: 9781621000273ISBN 10: 1621000273 Pages: 200 Publication Date: 09 October 2012 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Available To Order ![]() We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsPreface; Neuropathology of human prion diseases; The nature of the infectious agents: PrP models of resistant species to prion diseases (dog, rabbit & horses); Inducing transmissible prion diseases with recombinant fibrils: a new concept on genesis & evolution of infectious prions; Synthetic prions; Recent development in cell biology: role of glycosylation in prion diseases; Transmissibility of prion diseases in rodent models: atypical strains; Pre-Mortem Diagnostic Screening for Transmissible Spongiform Encephalopathies by Proteomic Approaches; Added value of biochemical tools for the diagnosis of human prion disease; Anti-prion strategies for in vivo gene therapy; Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |