Overview

This volume is a new edition of the most authoritative book on Prion Biology, first published in 1999 and edited by the Nobel Prize-winning founder of the field. This expanded edition has been completely updated, and includes chapters on therapeutics, and diagnostic methods and approaches.

Full Product Details

Author:   Stanley B. Prusiner (University of California, San Francisco, California, USA)
Publisher:   Cold Spring Harbor Laboratory Press,U.S.
Imprint:   Cold Spring Harbor Laboratory Press,U.S.
Edition:   2nd Revised edition
Volume:   No. 41
Dimensions:   Width: 16.50cm , Height: 5.10cm , Length: 23.50cm
Weight:   1.874kg
ISBN:  

9780879696931

ISBN 10:   0879696931
Pages:   1050
Publication Date:   15 December 2003
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

PRION BIOLOGY An Introduction to Prion Biology and Diseases Chapter 1: S.B. Prusiner Chapter 2: Development of the Prion Concept S.B. Prusiner Chapter 3: Bioassays of Prions S.B. Prusiner, J. Safar, and S.J. DeArmond Chapter 4: Transmission and Replication of Prions S.B. Prusiner, M.R. Scott, S.J. DeArmond, and G. Carlson Chapter 5: Structural Studies of Prion Proteins C. Govaerts, H. Wille, S.B. Prusiner, and F.E. Cohen Chapter 6: Doppel, a New PrP-like Mammalian Protein D. Westaway, L.E. Hood, and S.B. Prusiner FUNGAL PRIONS Chapter 7: Prions of Yeast and Filamentous Fungi: [URE3], [PSI+], [PIN+], and [Het-s] R.B. Wickner, S.W. Liebman, and S.J. Saupe TRANSGENETICS AND CELL BIOLOGY OF PRIONS Chapter 8: Knockouts, Knockins, Transgenics, and Transplants in Prion Research E. Flechsig, J.C. Manson, R. Barron, A. Aguzzi, and C. Weissmann Chapter 9: Transgenetic Investigations of the Species Barrier and Prion Strains M. Scott, D. Peretz, R.M. Ridley, H.F. Baker, S.J. DeArmond, and S.B. Prusiner Chapter 10: Cell Biology of Prions D.A. Harris, P.J. Peters, A. Taraboulos, V. Lingappa, S.J. DeArmond, and S.B. Prusiner PRION DISEASES IN ANIMALS Chapter 11: Scrapie, Chronic Wasting Disease, and Transmissible Mink Encephalopathy S.B. Prusiner, E. Williams, J.-L. Laplanche, and M. Shinagawa Chapter 12: Bovine Spongiform Encephalopathy and Related Diseases G.A.H. Wells and J.W. Wilesmith HUMAN PRION DISEASES Chapter 13: Infectious and Sporadic Prion Diseases R.G. Will, M.P. Alpers, D. Dormont, and L.B. Schonberger Chapter 14: Inherited Prion Diseases Q. Kong, W.K. Surewicz, R.B. Petersen, W. Zou, S.G. Chen, P. Gambetti, P. Parchi, S. Capellari, L. Goldfarb, P. Montagna, E. Lugaresi, P. Piccardo, and B. Ghetti Chapter 15: Neuropathology of Prion Diseases S.J. DeArmond, J.W. Ironside, E. Bouzamondo-Bernstein, D. Peretz, and J.R. Fraser METHODOLOGY, BIOSAFETY, AND THERAPEUTICS Chapter 16: Some Strategies and Methods for the Study of Prions S.B. Prusiner, G. Legname, S.J. DeArmond, F.E. Cohen, J. Safar, D. Riesner, and K. Kaneko Chapter 17: Biosafety Issues in Prion Diseases H. Baron, J. Safar, D. Groth, S.J. DeArmond, and S.B. Prusiner Chapter 18: Therapeutic Approaches to Prion Diseases S.B. Prusiner, B.C.H. May, and F.E. Cohen Glossary Appendix Index

Reviews

Because of the increasing importance of prions to public health, and the burgeoning rate of discovery in prion biology, this is a timely occasion for a second edition of the book Prion Biology and Diseases. As with the first edition (published in 1999), the extensively revised and updated second edition is edited and substantially written by Stanley Prusiner. The book is comprehensive, authoritative, accessible and, for the most part, exciting to read. It will serve admirably as a standard of the new science of prionology for scientists, physicians and students. Nature Cell Biology The Editor hoped this book would stimulate and tempt young investigators to prion research. It certainly informs the novice that there is more to prions than mad cows and cannibals! And for the established researcher? This book should make a useful reference text as data from an extensive number of studies are contained within the same volume. Microbiology Today

Because of the increasing importance of prions to public health, and the burgeoning rate of discovery in prion biology, this is a timely occasion for a second edition of the book Prion Biology and Diseases. As with the first edition (published in 1999), the extensively revised and updated second edition is edited and substantially written by Stanley Prusiner. The book is comprehensive, authoritative, accessible and, for the most part, exciting to read. It will serve admirably as a standard of the new science of prionology for scientists, physicians and students. Nature Cell Biology The Editor hoped this book would stimulate and tempt young investigators to prion research. It certainly informs the novice that there is more to prions than mad cows and cannibals! And for the established researcher? This book should make a useful reference text as data from an extensive number of studies are contained within the same volume. Microbiology Today

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