Overview

Principles of Toxicology concisely and efficiently presents the scientific basis for toxicology as it applies to the workplace and the environment, covering diverse chemical hazards encountered in modern workplaces and natural environments and providing a practical understanding of these hazards for those concerned with protecting the health of humans and ecosystems. The work presents not only theory, but also practical information regarding chemical hazards to give the student and new professional a working knowledge of the practice of toxicology and the ability to solve problems in environmental and industrial settings. Case histories and examples from industrial and environmental exposures to chemicals are included to demonstrate the application of toxicological principles. To allow for seamless reader comprehension and further exploration of covered topics, the work is supplemented with numerous illustrations to clarify and summarize key points, as well as annotated bibliographies. In the 4th edition, all chapters and references have been updated to account for the latest scientific thinking, and new color figures have been added. New topics covered in 4th Edition of Principles of Toxicology include: Regulatory toxicology, including the key regulatory framework in which much of the field of toxicology operates Alternative methods in toxicology, including cutting-edge approaches to developing new information on the toxicity of drugs and chemicals The dilemma of selecting safe exposure limits, guiding readers through practical considerations and pitfalls in developing and using safe exposure limits Ecological risk assessment, with detailed discussion of methods and considerations when evaluating the effects of contaminants on plants and animals. Providing information on the principles of toxicology and the application of those principles to solve problems in environmental and industrial settings, Principles of Toxicology serves as an excellent textbook resource for advanced undergraduate, graduate, and professional students in a range of environmental and health fields. It is also valuable to health professionals who need toxicological information and assistance beyond what is found in an introductory text to general toxicology.

Full Product Details

Author:   Stephen M. Roberts (Center for Environmental and Human Toxicology, University of Florida, Gainesville, Florida, USA) ,  Robert C. James (ToxStrategies, Boise, ID ) ,  Phillip L. Williams (College of Public Health, University of Georgia, Athens, Georgia, USA)
Publisher:   John Wiley & Sons Inc
Imprint:   John Wiley & Sons Inc
Edition:   4th edition
Dimensions:   Width: 21.80cm , Height: 3.10cm , Length: 27.40cm
Weight:   1.406kg
ISBN:  

9781119635178

ISBN 10:   1119635179
Pages:   592
Publication Date:   15 April 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Available To Order  
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

Table of Contents

1 General Principles of Toxicology Robert C. James, Stephen M. Roberts, and Phillip L. Williams 2 Xenobiotic Absorption, Distribution, Metabolism and Excretion Michael R. Franklin 3 Toxicokinetics Rebecca A. Clewell and Harvey J. Clewell III 4 Regulatory Toxicology Raymond M. David 5 Alternative Methods in Toxicity Testing Leona D. Scanlan, XuefeiCao, and Christopher D. Vulpe 6 ComputationalToxicology Richard S. Judson, David M. Reif, Keith A. Houck, Thomas B. Knudsen, Joshua Harrill, Katie Paul Friedman 7 Hematotoxicity:Toxic Effects on the Hematopoietic System Lila Ramaiah, Tara Arndt, and Michelle Cora 8 Hepatotoxicity: Toxic Effects on the Live Robert C. James and Stephen M. Roberts 9 Nephrotoxicity: Toxic Effects on the Kidney Lawrence H. Lash 10 Neurotoxicology: Toxic Effects on the Nervous System W. Michael Caudle, Meghan Bucher, Alexandria C. White, and Gary W. Miller 11 Dermal Toxicology: Toxic Effects on the Skin Sailesh Konda and Howard I Maibach 12 Pulmonotoxicity: Toxic Effects on the Respiratory System Cuiqing Liu and Qinghua Sun 13 Immunotoxicity: Toxic Effects on the Immune System Eric S. Sobel and Stephen M. Roberts 14 Reproductive and Developmental Toxicity: Toxic Effects on the Female and Male Reproductive Tracts and Offspring Shuo Xiao, Krista Symosko, and Charles A. Easley IV 15 Mutagenesis and Genetic Toxicology Martha M. Moore, Meagan B. Myers and Robert H. Heflich 16 Chemical Carcinogenesis James E. Klaunig, Luma Melo, and Karen Tilmant 17 Properties and Effects of Metals David B. Mayfield, Lisa A. Bailey, Joel M. Cohen, and Barbara D. Beck 18 Pesticides Janice Britt 19 Properties and Toxicology of Organic Solvents and Solvent-Like Chemicals Christopher M. Teaf and Michele M. Garber 20 Nanotoxicology Hongbo Ma and Stephen M. Roberts 21 Insights into Epidemiology J. Fryzek, C. Frankenfeld, N. Movva, L. Bylsma, and J. Acquavella 22 Occupational and Environmental Health Laura Breeher, Fredric Gerr, and T. Renėe Anthony 23 Human Health Risk Assessment Leah D. Stuchal 24 Ecological Risk Assessment Brett Thomas 25 The Dilemma of Selecting Safe Exposure Values Robert C. James, Phillip L. Williams,and Stephen M. Roberts

Reviews

Author Information

Stephen M. Roberts, PhD, is Professor and Program Director of the Center for Environmental and Human Toxicology at the University of Florida, Gainesville, FL. Robert C. James, PhD, is Senior Science Advisor, ToxStrategies, Boise, ID. Phillip L. Williams, PhD, is Dean and Professor Emeritus, College of Public Health, University of Georgia, Athens, GA.

Tab Content 6

Author Website:  

Countries Available

All regions