|
![]() |
|||
|
||||
OverviewX-ray crystallography is an established method for studying the structure of proteins and other macromolecules. As the importance of proteins grows, researchers in many fields have found that a working knowledge of X-ray diffraction is an indispensable tool. In this new edition of his essential work, the internationally recognized researcher Dr. Jan Drenth offers an up-to-date and technically rigorous introduction to the subject, providing the theoretical background necessary to understand how the structure of proteins is determined at atomic resolution. New material in the 3rd edition includes a section on twinning, an additional chapter on crystal growth and a discussion of single-wavelength anomalous dispersion. Full Product DetailsAuthor: Jan DrenthPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 3rd ed. 2007 Dimensions: Width: 15.50cm , Height: 2.00cm , Length: 23.50cm Weight: 1.470kg ISBN: 9780387333342ISBN 10: 0387333347 Pages: 332 Publication Date: 09 November 2006 Audience: College/higher education , Professional and scholarly , Undergraduate , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsCrystallizing a Protein.- X-ray Sources and Detectors.- Crystals.- Theory of X-ray Diffraction by a Crystal.- Average Reflection Intensity and Distribution of Structure Factor Data.- Special Forms of the Structure Factor.- The Solution of the Phase Problem by the Isomorphous Replacement Method.- Phase Improvement.- Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration.- Molecular Replacement.- Direct Methods.- Laue Diffraction.- Refinement of the Model Structure.- The Combination of Phase Information.- Checking for Gross Errors and Estimating the Accuracy of the Structural Model.- Practical Protein Crystallization.ReviewsFrom the reviews of the third edition: <p> This book, Principles of Protein X-ray Crystallography, aims to satisfy nearly everyone; a ] The volume is well organized a ] . this is a solid book by an experienced protein crystallographer. It covers the full spectrum of subjects for a professional structural biologist. Specialized subjects are kept in separate chapters so the book can be parsed by those interested in the big picture of the method. a ] it is probably the most definitive work that is currently available for structural biologists. (Jon Robertus, Journal of the American Chemical Society, Vol. 129 (17), 2007) From the reviews of the third edition: This book, Principles of Protein X-ray Crystallography, aims to satisfy nearly everyone; ... The volume is well organized ... . this is a solid book by an experienced protein crystallographer. It covers the full spectrum of subjects for a professional structural biologist. Specialized subjects are kept in separate chapters so the book can be parsed by those interested in the big picture of the method. ... it is probably the most definitive work that is currently available for structural biologists. (Jon Robertus, Journal of the American Chemical Society, Vol. 129 (17), 2007) Author InformationDr. Jan Drenth is a professor emeritus at the Laboratory of Biophysical Chemistry at the University of Groningen, The Netherlands. Contributing author Dr. Jeroen R. Mesters Ph.D. is a Senior Research Assistant at the Institute of Biochemistry, University of Luebeck, Germany. Tab Content 6Author Website:Countries AvailableAll regions |