Overview

With nearly 400 original illustrations, this NMR primer provides an introduction to solution NMR spectroscopy at a level appropriate for advanced undergraduates, graduate students and working scientists with backgrounds in chemistry or biochemistry. It presents the underlying physics and mathematics in a way that is both accessible and sufficiently complete to allow a real understanding of modern multi-dimensional experiments, thereby giving readers the tools they need to move to more advanced textbooks and articles. One special feature of this text is a thorough, but accessible, treatment of spin quantum mechanics, including scalar-coupled spins. A novel style of vector diagram is used to represent the quantum correlations between coupled spins and the manipulation of these correlations by pulses and time evolution. This will help to clarify what is arguably the most difficult aspect of NMR for students and practitioners to master.

Full Product Details

Author:   David Goldenberg
Publisher:   Macmillan Education UK
Imprint:   Red Globe Press
Edition:   Softcover reprint of the original 1st ed. 2016
ISBN:  

9781349958054

ISBN 10:   1349958050
Pages:   500
Publication Date:   11 February 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1. An Overview of Modern Solution NMR.- 2. An Introduction to Spin and Nuclear Magnetism.- 3. Early NMR Experiments.- 4. Chemical Information from Resonance Frequencies.- 5. The Pulse NMR Methods: The Pulse.- 6. The Pulse NMR Method: The Signal and Spectrum.- 7. Relaxation.- 8. A More Mathematical Look at Relaxation.- 9. Cross Relaxation and the Nuclear Overhauser Effect.- 10. Two-dimensional NMR Experiments.- 11. The Mathematical Formalism of Quantum Mechanics.- 12. More Quantum Mechanics: Time and Energy.- 13. Quantum Description of a Scalar-coupled Spin Pair.- 14. NMR Spectroscopy of a Weakly-coupled Spin Pair.- 15. Two-dimensional Spectra Based on Scalar Coupling.- 16. Heteronuclear NMR Techniques.- 17. Introduction to the Density Matrix.- 18. The Product-operator Formalism.- Appendix A: List of Symbols, Numerical Constants and Abbreviations.- Appendix B: Trigonometric Functions and Complex Numbers.- Appendix C: Fourier Series and Transforms.- Appendix D: Vectors and Matrices.- Appendix E: Mathematics for Uncoupled Spin-1/2 Particles.- Appendix F: Mathematics of the Two-spin System.- Index.

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Author Information

David P. Goldenberg is a Professor of Biology at the University of Utah, where he teaches and researches subjects in the general areas of biochemistry and biophysics, especially protein folding, dynamics and function. He received an A.B. degree in Chemistry and Mathematics from Whitman College in 1976 and a Ph.D. in Biology from the Massachusetts Institute of Technology in 1981. Before moving to the University of Utah, he was a post-doctoral associate at the Medical Research Laboratory of Molecular Biology, in Cambridge, England.

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