Overview

This is the first major textbook of molecular medicine to integrate the newest findings from cell and molecular biology with the basic principles of internal medicine. J. Larry Jameson, MD and his authoritative contributors, many of them world-renowned clinicians and researchers, expand the envelope of clinical understanding to encompass a wide array of disciplines-including neurology, cardiology, hematology, nephrology, genetics, endocrinology, oncology, dermatology, psychiatry, and infectious diseases-revealing the underlying molecular mechanisms of disease, as well as the routes to unprecedented novel medicines and treatments now emerging from the new molecular approaches. Here physicians will find informative updates in both their own specialties and in disciplines they may not have been able to follow closely. They will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more. This groundbreaking and uniquely valuable new approach to human medical biology will provide practicing physicians, medical students, and researchers alike with a powerful new account of internal medicine and help them to better understand the future of medicine.

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9781280358340

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Reviews

Winner of the Book of the Year Award from Doody's Health Science Book Review Journal<br> The selection of topics, the ability of the contributors to present complex topics in a clear, concise manner, and the format should all contribute to making this book the standard text and reference in its field. It should be in the collection of every medical library and on the bookshelf of every physician interested in keeping up with the transformation of medicine by molecular genetics. 5 Stars-Doody's Health Science Book Review Journal. <br> .,. bridge[s] the current gap between basic science and the bedside. It will thus be useful to researchers and clinicians alike. With more than 100 chapters covering a wide variety of topics, its distinguished cohort of section editors, and its abundant tables and illustrations, it provides an accessible and much needed manual to the present and the future of molecular genetics. -Francis S. Collins, MD, PhD <br> .,. a first-class reference textbook. The format of this book is easy to follow and is relevant to the way in which medicine is currently practiced. Its division into the traditional disciplines of medicine makes it easy to identify how molecular developments have enhanced our medical knowledge, diagnostic potentials and therapeutic options...The editor-in-chief, his section editors and the contributing authors should all be congratulated on a superb job. -Molecular Medicine Today <br> Because molecular medicine has already started to become an integral part of medical practice, there is a growing need to integrate it into the medical school curriculum and medical education in general. Principles of Molecular Medicine is well suited to servingthis purpose. . .closing the gap between basic science and the bedside. The book is organized according to organ systems and comprises more than 120 chapters, each written by outstanding specialists. . .The various facets of human hereditary disorders, including genetic counseling and molecular diagnostic testing, are clearly and comprehensively presented. . .the book is well written and attractive. . .[and] is a valuable resource that will certainly appeal to clinicians, researchers, teachers, and students alike. It will also be of value to those involved in a particular area of molecular medicine who need a reference manual in which to find information on aspects of the field in which they are less familiar. . .a valuable reference for anyone with an interest in the achievements and the potential of molecular medicine. -Michael Goosens, MD review in the May 20, 1999 issue of the New England Journal of Medicine<br>

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