Overview

Beginning in the 1960s, scientists across a wide range of disciplines co-operated in developing unbiased - or assumption-free - stereology, based on stochastic geometry and probability theory, as a way to estimate the parameters of irregularly shaped objects without introducing bias. In recent years these new estimation techniques, which were originally quite painstaking and time consuming, have made a great deal of headway in disciplines such as neuroscience, thanks in part to the development of computer software for their application. Prestigious journals and grant-giving organizations now require the use of unbiased stereology in the projects that they support, and this trend is expected to continue. This volume is intended to fill the need in the biomedical community for a clear, user-friendly introduction to this area for the increasing number of scientists who need to learn these techniques for their research. The work moves logically from a discussion of the historical background of stereology to full explanations of terms, concepts and tools, with the latter part of the manuscript devoted to typical stereology designs. An associated website offers colour illustrations and video clips demonstrating stereological techniques.

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9780801867972

Table of Contents

Reviews

<p>This is an important book for the libraries of professionals in neurobiology, neurology, and neurosurgery.--Celso Agner Doody's Health Sciences Review

<p> This book is a valuable addition to the current literature on stereologic methods. Beginners will find it useful and easy to read. The text will also offer an excellent support for stereology courses as it provides the reader with sufficient technical background without being overwhelming with mathematical details, and is designed for a 'hands-on' approach to learning stereologic methods, unlike other books on the subject. The author's expertise is in neurobiology and neuropathology, but clearly this book is not targeting only 'neurostereologists'; investigators from all domains of biology, as well as geologists, material scientists, and engineers, will benefit from reading and using it. -- Patrick R. Hof, Mount Sinai School of Medicine

This is an important book for the libraries of professionals in neurobiology, neurology, and neurosurgery. -- Celso Agner Doody's Health Sciences Review

Author Information

Peter R. Mouton, Ph.D., is director and CEO of the Stereology Resource Center, Inc., and consulting director of the Stereology Laboratory at the Laboratory of Neurosciences Gerontology Research Center, NIA/NIH, in Baltimore.

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