Overview

Consisting of contributions from experts in all specialties of cardiovascular genetics and applied clinical cardiology, Principles and Practice of Clinical Cardiovascular Genetics serves as the comprehensive volume for any clinician or resident in cardiology and genetics. Each chapter provides a detailed and comprehensive account on the molecular genetics and clinical practice related to specific disorders or groups of disorders, including Marfan syndrome, thoracic and abdominal aortic aneurysms, hypertrophic, dilated and restrictive cardiomyopathies and Arrhythmogenic right ventricular cardiomyopathy, as well as many others. All sections comprehensively address cardiovasuclar genetic disorders, beginning with an introduction and including separate sections on the disease's basic biological aspects, specific genetic mechanisms or issues, clinical aspects, genetic management (e.g., genetic diagnosis, risk assessment, genetic counseling, genetic testing), and clinical management issues. The final section exclusively addresses the management of cardiovascular genetic disorders, specifically considering stem cell therapy, genetic counseling, pharmacogenomics and the social and ethical issues surrounding disease treatment.

Full Product Details

Author:   Dhavendra Kumar ,  Perry Elliott
Publisher:   Oxford University Press Inc
Imprint:   Oxford University Press Inc
Dimensions:   Width: 28.20cm , Height: 3.80cm , Length: 21.80cm
Weight:   2.220kg
ISBN:  

9780195368956

ISBN 10:   0195368959
Pages:   624
Publication Date:   29 April 2010
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Foreword: Professor Eric Topol, San Diego, USA Introduction: Clinical Cardiovascular Genetics, Dhavendra Kumar and Perry Elliott Section A: General aspects of cardiovascular genetics 1. Development of the heart, Robert H. Anderson, Nigel Brown, Antoon F. M. Moorman 2. Molecular basis of cardiovascular development, Jamie Bentham, Shoumo Bhattacharya 3. Classification of inherited cardiovascular conditions, Dhavendra Kumar 4. Genetic epidemiology of cardiovascular disease, Teri A. Manolio and Elizabeth G Nabel 5. Cytogenetic testing in cardiovascular genetics, Helen Cox 6. Molecular diagnosis in cardiovascular genetics, Karen Maresso, Michael Harrison, Ulrich Broeckel and Ian Frayling 7. Cardiac magnetic resonance imaging in cardiovascular genetics , James Moon 8. Ultrasound imaging in cardiovascular genetics, Denis Pellerin, Diala Khraiche Section B: Specific cardiovascular genetic disorders 9. Congenital cardiovascular malformations, Judith Goodship and Christopher Wren 10. Malformation syndromes with heart disease, Michael A. Patton 11. Marfan syndrome and related disordersm, John C. S. Dean, Sally Davies, Bart Loeys 12. Thoracic and abdominal aortic aneurysms, Susan Drinkwater, Dhavendra Kumar, Peter Taylor 13. Hypertrophic, dilated and restrictive cardiomyopathies, Juan Pablo-Kaski, Perry M. Elliott 14. Arrhythmogenic right ventricular cardiomyopathy, Petros Syrris, William J. McKenna 15. Ventricular non-compaction, Girish Dwivedi, Ibrar Ahmed, Zaheer Yousef, Michael Frenneaux 16. Molecular genetics of arrhythmias, Seo-Kyung Chung. Jonathan R. Skinner, Mark I. Rees 17. Long QT syndrome and cathecholaminergic polymorphic ventricular tachycardia, Tom Rossenbacker, Carlo Napolitano, Sylvia G. Priori 18. Acquired repolarization disorders, Elijah R. Behr, John Camm 19. Brugada syndrome, Pieter G. Postema, Pascal F.H.M. van Dessel, Arthur Wilde 20. Inherited conduction disease and familial AF, Calum A. MacRae 21. Familial hypercholesterolemia, Ian F. W. McDowell, S. Gaye Hadfield, Steve E. Humphries 22. Genetics of Coronary artery disease, Yoshiji Yamada, Sahoko Ichihara, Tamotsu Nishida 23. Genetics of essential hypertension, Mark Caulfield, Stephen J. Newhouse and Patricia B. Munroe 24. Stroke, Yoshiji Yamada, Sahoko Ichihara, Tamotsu Nishida 25. Pulmonary arterial hypertension, J.R. Thompson, R.C. Trembath 26. Heart and Metabolic disease, Mike Champion, Maureen Cleary 27. Heart and neuromuscular disease, John P. Bourke and Kate M.D. Bushby 28. Heart and genetic collagen disorders, Mike Pope 29. Heart and inherited disorders of hemoglobin, Malcolm J Walker and Constantinos O'Mahony 30. Familial Amyloidoses and the Heart, Claudio Rapezzi, Candida Cristina Quarta, Letizia Riva, Fabrizio Salvi, Paolo Ciliberti, Simone Longhi, Elena Biagini 31. Cardiac involvement in mitochondrial disease, Patrick F. Chinnery, Grainne Gorman 32. Inherited cardiac tumors, D. Mark Davies Section C: Management of cardiovascular genetic diseases 33. The sudden arrhythmic death syndrome, Pier D. Lambiase 34. Cardiovascular pharmacogenomics, Martin C. Michel and Dieter Rosskopf 35. Stem cell therapy in cardiovascular medicine, Shinsuke Yuasa, Keiichi Fukuda 36. Genetic counseling in cardiovascular genetics, Ivan Macciocca 37. Social and ethical issues in cardiovascular genetics, Angus Clarke and Siv Folkstuen 38. Forensic pathologist and genetic cardiovascular disease: A UK perspective, Stephen Leadbeatter 39. Provision of clinical cardiovascular genetic services, Paul Brennan

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